The antibody clone SH1429_B1 was produced by immunizing with full length TcdB from Clostridioides difficile. It can be used for detection of Clostridioides difficile TcdB in ELISA and WB assays.
Figure 1 IC50 of ViF087_A10 and SH1429_B1 were estimated with serial antibody dilutions.
TcdBFL neutralization of ViF087_A10 and SH1429_B1 was further verified using serial dilutions of these antibodies
Figure 2 Antigen ELISA on TcdB variants of SH1429_B1 and SH1429_B10.
The one most potent neutralizing antibodies (SH1429_B1) bind to epitopes within TcdB1−1852.
Figure 3 In vitro neutralization of TcdB including antibody SH1429_B1.
Figure 4 In vitro neutralization of TcdB with antibody combinations. TcdB (0.1 pM) and 0.1 nM SH1429_B1 mAbs were coincubated in cultivation media with 100 nM of CROPs binding mAbs.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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MRO-153CT-S(P) | Human Anti-TcdB Recombinant Antibody; scFv Fragment (MRO-153CT-S(P)) | WB, ELISA, Neut | Human scFv |
MRO-154CT-S(P) | Human Anti-TcdB Recombinant Antibody; scFv Fragment (MRO-154CT-S(P)) | WB, ELISA, Neut | Human scFv |
MRO-155CT-S(P) | Human Anti-TcdB Recombinant Antibody; scFv Fragment (MRO-155CT-S(P)) | WB, ELISA, Neut | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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