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    CytoStream™ Rabbit Anti-TCF7L2 Recombinant Antibody (VS13-YC1148) (CAT#: VS13-YC1148)

    The CytoStream™ Rabbit Anti-TCF7L2 Recombinant Antibody is specific for human and mouse TCF7L2. TCF7L2 encodes a transcription factor in the Wnt signaling pathway, regulating blood glucose homeostasis, with variants associated with type 2 diabetes risk. The anti-TCF7L2 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).

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    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-251 MG
    Figure 1 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm, nuclear bodies & cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/38800/789_D12_2_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human duodenum
    Figure 2 IHC staining of human duodenum
    (Immunohistochemical staining of human duodenum shows strong nuclear and cytoplasmic positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/13535/ihc_selected.jpg
    Figure 3 Cerebral cortex
    Figure 3 Cerebral cortex
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/13535/30323_B_7_5.jpg
    Figure 4 Small intestine
    Figure 4 Small intestine
    (Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/13535/30323_A_4_2.jpg
    Figure 5 Colon
    Figure 5 Colon
    (Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/13535/30323_A_7_3.jpg
    Figure 6 Liver
    Figure 6 Liver
    (Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: nuclear Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/13535/30323_A_7_4.jpg
    Figure 7 Kidney
    Figure 7 Kidney
    (Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/13535/30323_A_8_5.jpg
    Figure 8 Testis
    Figure 8 Testis
    (Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Peritubular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Spermatogonia cells Staining: High Intensity: Strong)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/13535/30323_A_5_6.jpg
    Figure 9 Lymph node
    Figure 9 Lymph node
    (Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/13535/30323_A_9_8.jpg
    RNA Expression
    Figure 10 RNA cell line category: Low cell line specificity
    Figure 10 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000148737-TCF7L2

    Specifications

    • Immunogen
    • Recombinant human TCF7L2, aa 1-49.
    • Host Species
    • Rabbit
    • Type
    • Rabbit IgG
    • Specificity
    • Human and Mouse TCF7L2
    • Species Reactivity
    • Human, Mouse
    • Applications
    • WB, ICC, IF, IHC-P, IP, FC
    • Conjugate
    • NONE

    Product Property

    • Clonality
    • Monoclonal
    • Purification
    • Protein A purified
    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
    • Preservative
    • 0.05% Sodium azide
    • Storage
    • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Shipping with ice pack.

    Applications

    • Application Notes
    • Western blot (WB): 1/500-1/1000
      Immunocytochemistry (ICC): 1/50-1/200
      Immunofluorescence (IF): 1/50-1/200
      Immunohistochemistry-paraffin (IHC-P): 1/50-1/200
      Flow cytometry (FC): 1/50-1/100

    Target

    • Alternative Names
    • Transcription Factor 7 Like 2; Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box); T-Cell-Specific Transcription Factor 4; HMG Box Transcription Factor 4; T-Cell Factor 4; HTCF-4; TCF-4; TCF4; Transcription Factor 7-Like 2;
    • Long Name
    • Transcription Factor 7 Like 2
    • Cellular Localization
    • Nucleus

    Recommended Products

    Secondary Antibody

    Isotype Control

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "TCF7L2"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products Rabbit Monoclonal Antibody Products
    CAT Product Name Application Type
    MOB-0828CT Recombinant Mouse anti-Human TCF7L2 Monoclonal antibody (EML1831) WB
    MRO-1476-CN Rabbit Anti-TCF7L2 Recombinant Antibody (clone CBACN-549) WB, IF, IHC, IP, FC Rabbit IgG
    VS3-WK1167 Rabbit Anti-TCF7L2 Recombinant Antibody (VS3-WK1167) WB, ELISA Rabbit IgG

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