Human Anti-TCIRG1 Antibody (Metiliximab), CHO Stable Cell Pool
CAT#: VS-1025-QX254
This CHO Stable Cell Pool represents a genetically engineered Chinese Hamster Ovary (CHO) cell population specifically designed for the robust and consistent expression of recombinant Metiliximab. Metiliximab is a Human monoclonal antibody that targets TCIRG1. This cell pool was generated through the stable integration of genes encoding the heavy and light chains of Metiliximab into the CHO genome, followed by selection and enrichment for high-expressing cells. This cell pool provides rapid production of research-grade antibodies for non-GLP preclinical studies.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38742/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human bone marrow
Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in hematopoietic cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38742/86587_B_6_4_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38742/86587_B_8_5.jpg
Normal Tissue
Figure 4 Lung
Macrophages Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38742/86587_A_2_4.jpg
Normal Tissue
Figure 5 Colon
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38742/86587_A_7_3.jpg
Normal Tissue
Figure 6 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38742/86587_A_9_5.jpg
Normal Tissue
Figure 7 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38742/86587_A_4_6.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (HMC-1, RPMI-8226)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000110719-TCIRG1
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Specifications
- Host Cell
- CHO
- Product Type
- Stable Cell Pool
- Cell Viability
- >90%
- Mycoplasma Detection
- Negative
- Bacteria Detection
- Negative
- Growth Properties
- Suspension
- Culture Medium
- VersaCHO™ Medium (VS-1025-QX582)
- Complete Growth Medium
- VersaCHO™ Medium (VS-1025-QX582), VersaCHO™ Feed Medium (VS-1025-QX583), VersaCHO™ Feed Supplement (VS-1025-QX584)
- Freeze Medium
- 90% VersaCHO™ Medium, 10% DMSO
- Growth Conditions
- 37°C, 5% CO₂
- Size
- Each vial contains at least 1×10^6 cells in 1 mL
- Shipping
- Dry ice
- Storage
- Store in liquid nitrogen immediately upon receipt. Avoid multiple freeze/thaw cycles. Utilize cells within one year of the delivery date.
Antibody Overview
- Host Species
- Human
- Antibody Type
- Human IgG1, κ
- Clone
- Metiliximab
- Target
- TCIRG1
- Species Reactivity
- Human
Target
- Alternative Names
- TCIRG1; Vacuolar Proton Translocating ATPase 116 KDa Subunit A Isoform 3; T-Cell, Immune Regulator 1; V-ATPase 116-KDa; Specific 116-KDa Vacuolar Proton Pump Subunit; V-Type Proton ATPase 116 KDa Subunit A; V-ATPase 116 KDa Isoform A3; T-Cell Immune Respo
- Gene ID
- 10312
- UniProt ID
- Q13488
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "Clone Metiliximab"
- CAT
- Product Name
See other products for "TCIRG1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3563z | Mouse Anti-TCIRG1 Recombinant Antibody (MOB-3563z) | WB, IP, ELISA | Mouse IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3563z-F(E) | Recombinant Anti-Human TCIRG1 Antibody Fab Fragment | IF, Neut, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3563z-S(P) | Recombinant Anti-Human TCIRG1 Antibody scFv Fragment | IP, IF, Biosensors, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1912MZ | Recombinant Mouse Anti-Human TCIRG1 Antibody (clone 6H3) | WB | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0340-WJ | Human Anti-TCIRG1 Recombinant Antibody (clone Metiliximab) | ELISA | Humanized IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0341-WJ | Human Anti-TCIRG1 Recombinant Antibody (clone Neliximab) | ELISA | Humanized IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0340-WJ-S(P) | Human Anti-TCIRG1 Recombinant Antibody (clone Metiliximab); scFv Fragment | ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0341-WJ-S(P) | Human Anti-TCIRG1 Recombinant Antibody (clone Neliximab); scFv Fragment | ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0340-WJ-F(E) | Human Anti-TCIRG1 Recombinant Antibody (clone Metiliximab); Fab Fragment | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0341-WJ-F(E) | Human Anti-TCIRG1 Recombinant Antibody (clone Neliximab); Fab Fragment | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC578 | Recombinant Anti-TCIRG1 Vesicular Antibody, EV Displayed (VS-0425-YC578) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7142 | Anti-TCIRG1 Immunohistochemistry Kit | IHC |
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