Mouse Anti-TCL1A Recombinant Antibody (clone 2E3A5) (CAT#: VS7-0425-WR959)
This product is a mouse IgG1 antibody that binds to human TCL1A. The antibody 2E3A5 recognizes specific amino acid domain of human TCL1A (AA: 10-104) . It can be used for FC assay.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line REH
(Immunofluorescent staining of human cell line REH shows localization to nucleoplasm, cytosol & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16604/1778_H1_6_selected.jpg
(Immunofluorescent staining of human cell line REH shows localization to nucleoplasm, cytosol & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16604/1778_H1_6_selected.jpg
Figure 2 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16604/37654_A_9_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16604/37654_A_9_8.jpg
Figure 3 Tonsil
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16604/37654_A_4_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16604/37654_A_4_8.jpg
Figure 4 RNA cell line category: Group enriched (Daudi, REH, U-698)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000100721-TCL1A
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000100721-TCL1A
Specifications
- Immunogen
- Recombinant human TCL1A (AA: 10-104) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human TCL1A
- Species Reactivity
- Human
- Clone
- 2E3A5
- Molecule Class
- Proto-Oncogene
- Applications
- FC
- Conjugate
- Unconjugated
- Related Disease
- Chromosomal aberrations activating TCL1A are found in chronic T-cell leukemias (T-CLL). Translocation t(14;14)(q11;q32); translocation t(7;14)(q35;q32); inversion inv(14)(q11;q32) that involves the T-cell receptor alpha/delta loci
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- TCL1A; Oncogene TCL-1; Oncogene TCL1; T-Cell Lymphoma-1; Protein P14 TCL1; T-Cell Leukemia/Lymphoma Protein 1A; T-Cell Leukemia/Lymphoma 1A
- Gene ID
- 8115
- UniProt ID
- P56279
- Long Name
- TCL1A Gene(Protein Coding) T Cell Leukemia/Lymphoma 1A
- Cellular Localization
- Cytoplasm; Endoplasmic reticulum; Microsome; Nucleus
- Protein Refseq
- NP_001092195.1
- Function
- Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival.
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "TCL1A"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products
Chicken IgY Antibody Products
Rabbit Monoclonal Antibody Products
MHC Tetramer Products for Cancer
Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1913MZ | Recombinant Mouse Anti-Human TCL1A Antibody (clone 2-32) | FC, IHC-P, IP, WB | Mouse antibody |
| ZG-0112C | Mouse Anti-TCL1A Recombinant Antibody (clone ABT-TCL1) | IHC-P, IF | Mouse IgG |
| ZG-0113C | Mouse Anti-TCL1A Recombinant Antibody (clone PT0243) | IHC-P, IF | Mouse IgG |
| VS3-QX1088 | Mouse Anti-TCL1A Recombinant Antibody (clone 5E-3A) | WB, FC | Mouse IgG1 |
| VS3-CJ1051 | Mouse Anti-TCL1A Recombinant Antibody (VS3-CJ1051) | IHC | Mouse IgG1 |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS7-0425-WR959. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, IHC
-1.png)
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, FC, WB, FuncS
Application: ELISA, FuncS, IHC, IF, FC, ADCC
Application: ELISA
Application: Neut, ELISA, FuncS
Application: ELISA, Inhib, FuncS
Application: ELISA, FC, IF, IHC, WB
Application: ELISA, Block, WB, FC, IP
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
