Mouse Anti-TCR Recombinant Antibody (clone 1B2) (CAT#: FAMAB-0110-CN)

The mAb 1B2 is a clonotypic mouse monoclonal antibody specific for the 2C TCR. The antibody 1B2 binds to TCR with high affinity.


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ELISA

Figure 1 Effect of CDR3α mutations on binding to QL9/Ld, SIYR/Kb, and mAb 1B2.

Figure 1 Effect of CDR3α mutations on binding to QL9/Ld, SIYR/Kb, and mAb 1B2.

Effect of 2C TCR CDR3α mutations on binding the three different ligands at 4°C. Reactivity of CDR3α alanine mutants for SIYR/Kb tetramer complexes and mAb 1B2 was assessed in ELISAs as described in Materials and Methods. QL9/Ld reactivity was determined in a competition assay with 125I-labeled anti-Ld Fab fragments

Lee, P. U., Churchill, H. R., Daniels, M., Jameson, S. C., & Kranz, D. M. (2000). Role of 2C T Cell Receptor Residues in the Binding of Self–and Allo–Major Histocompatibility Complexes. Journal of Experimental Medicine, 191(8), 1355-1364.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG1
  • Specificity
  • Human TCR
  • Species Reactivity
  • Human
  • Clone
  • 1B2
  • Applications
  • ELISA, WB, FC

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Enzyme-Linked Immunosorbent Assay, Flow Cytometry and Western Blot.

Target

  • Alternative Names
  • TCR

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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Recombinant Antibody

Mouse Antibody

CAT Product Name Application Type
TAB-595CL Mouse Anti-TCR Recombinant Antibody (TAB-595CL) FuncS Mouse IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-248 Afuco™ Anti-TCR ADCC Recombinant Antibody (Maslimomab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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