The mAb 1B2 is a clonotypic mouse monoclonal antibody specific for the 2C TCR. The antibody 1B2 binds to TCR with high affinity.
Figure 1 Effect of CDR3α mutations on binding to QL9/Ld, SIYR/Kb, and mAb 1B2.
Effect of 2C TCR CDR3α mutations on binding the three different ligands at 4°C. Reactivity of CDR3α alanine mutants for SIYR/Kb tetramer complexes and mAb 1B2 was assessed in ELISAs as described in Materials and Methods. QL9/Ld reactivity was determined in a competition assay with 125I-labeled anti-Ld Fab fragments
Lee, P. U., Churchill, H. R., Daniels, M., Jameson, S. C., & Kranz, D. M. (2000). Role of 2C T Cell Receptor Residues in the Binding of Self–and Allo–Major Histocompatibility Complexes. Journal of Experimental Medicine, 191(8), 1355-1364.
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MOB-956 | Recombinant Anti-TCR Antibody | WB, ELISA, IHC, FuncS | IgG |
MHH-956 | Recombinant Human Anti-TCR Antibody | ELISA, WB, IP, FuncS | IgG |
TAB-558CT | Hamster Anti-TCR Recombinant Antibody (clone H57) | WB, FC | Hamster IgG |
HPAB-2571LY | Human Anti-TCR Recombinant Antibody (clone 15B4) | FC, ELISA | Humanized IgG |
HPAB-2572LY | Human Anti-TCR Recombinant Antibody (clone 5H4) | FC, ELISA | Humanized IgG |
CAT | Product Name | Application | Type |
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MOB-956-S(P) | Recombinant Anti-TCR Antibody scFv Fragment | Neut, WB, FuncS | scFv |
MHH-956-S(P) | Recombinant Human Anti-TCR Antibody scFv Fragment | FC, ELISA, FuncS | scFv |
TAB-558CT-S(P) | Hamster Anti-TCR Recombinant Antibody (clone H57); scFv Fragment | WB, FC | Hamster scFv |
HPAB-2571LY-S(P) | Human Anti-TCR Recombinant Antibody (clone 15B4); scfv Fragment | FC, ELISA | Humanized scfv |
HPAB-2572LY-S(P) | Human Anti-TCR Recombinant Antibody (clone 5H4); scfv Fragment | FC, ELISA | Humanized scfv |
CAT | Product Name | Application | Type |
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MHH-956-F(E) | Recombinant Human Anti-TCR Antibody Fab Fragment | WB, IP, FuncS | Fab |
TAB-558CT-F(E) | Hamster Anti-TCR Recombinant Antibody (clone H57); Fab fragment | WB, FC | Hamster Fab |
FAMAB-0109-CN-F(E) | Rat Anti-TCR Recombinant Antibody (clone KJ16); Fab Fragment | ELISA, IF, IP, WB, FC | Rat Fab |
HPAB-2571LY-F(E) | Human Anti-TCR Recombinant Antibody (clone 15B4); Fab Fragment | FC, ELISA | Humanized Fab |
HPAB-2572LY-F(E) | Human Anti-TCR Recombinant Antibody (clone 5H4); Fab Fragment | FC, ELISA | Humanized Fab |
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TAB-595CL | Mouse Anti-TCR Recombinant Antibody (TAB-595CL) | FuncS | Mouse IgG |
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TAB-545CT-S(P) | Anti-Human TCR Recombinant Antibody scFv Fragment (BMA 031) | ELISA, FC, WB | Humanized antibody |
TAB-546CT-S(P) | Anti-Human TCR Recombinant Antibody scFv Fragment (3H2906) | ELISA, FC, WB | Humanized antibody |
TAB-547CT-S(P) | Anti-Human TCR Recombinant Antibody scFv Fragment (IP26) | ELISA, FC, WB | Humanized antibody |
TAB-548CT-S(P) | Anti-Human TCR Recombinant Antibody scFv Fragment (T10B9) | ELISA, FC, WB | Humanized antibody |
TAB-549CT-S(P) | Anti-Human TCR Recombinant Antibody scFv Fragment (WT31) | ELISA, FC, WB | Humanized antibody |
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AFC-TAB-248 | Afuco™ Anti-TCR ADCC Recombinant Antibody (Maslimomab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
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