This product is a recombinant Human antibody that can recognize TFPI. mAb2F22, was raised against the N-terminal fragment of TFPI (1-79). mAb2F22 bound exclusively to the K1 domain of TFPI (KD ∼1 nm) and not to the K2 domain. mAb2F22 interfered with inhibition of both FVIIa and FXa activities and restored clot formation. mAb2F22 blocked TFPI inhibition of both FVIIa and FXa activities and mapped a FXa exosite for binding to K1.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-734 | Anti-TFPI Recombinant Antibody (Concizumab) | ELISA, IP, FC, FuncS, Neut, IF, WB | IgG4 - kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-0374MZ | Recombinant Mouse Anti-Human Tissue Factor Pathway Inhibitor Antibody (clone BIUGQJ-5139) | RIA, WB, ELISA | Mouse antibody |
MOB-2015CT | Recombinant Mouse anti-Human TFPI Monoclonal antibody (5H5) | ELISA, WB | |
HPAB-0476-CN | Mouse Anti-TFPI Recombinant Antibody (HPAB-0476-CN) | ELISA | Mouse IgG |
HPAB-0477-CN | Human Anti-TFPI Recombinant Antibody (HPAB-0477-CN) | ELISA, Neut | Chimeric (mouse/human) IgG1, κ |
HPAB-0478-CN | Human Anti-TFPI Recombinant Antibody (HPAB-0478-CN) | ELISA, Neut | Humanized IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-3547 | Rabbit Anti-TFPI Recombinant Antibody (clone DS3547AB) | WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBC-539 | Human Anti-TFPI Recombinant Antibody (clone ch2F22); Fab Fragment | ELISA, FC, Neut | Chimeric (mouse/human) Fab |
HPAB-2580LY-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-2580LY-F(E)) | ELISA, WB, FuncS | Human Fab |
HPAB-2581LY-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-2581LY-F(E)) | ELISA, WB, FuncS | Human Fab |
HPAB-2605LY-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-2605LY-F(E)) | ELISA, WB, FuncS | Human Fab |
HPAB-2606LY-F(E) | Human Anti-TFPI Recombinant Antibody; Fab Fragment (HPAB-2606LY-F(E)) | ELISA, WB, FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBC-539 | Human Anti-TFPI Recombinant Antibody (clone ch2F22); scFv Fragment | ELISA, FC, Neut | Mouse scFv |
HPAB-0495-YJ-S(P) | Human Anti-TFPI Recombinant Antibody; scFv Fragment (HPAB-0495-YJ-S(P)) | ELISA, WB, FuncS | Human scFv |
HPAB-0496-YJ-S(P) | Human Anti-TFPI Recombinant Antibody; scFv Fragment (HPAB-0496-YJ-S(P)) | ELISA, WB, FuncS | Human scFv |
HPAB-AP804-YC-S(P) | Human Anti-TFPI Recombinant Antibody (clone Antibody 1); scFv Fragment | ELISA, WB | Human scFv |
HPAB-AP805-YC-S(P) | Human Anti-TFPI Recombinant Antibody (clone Antibody 2); scFv Fragment | ELISA, WB | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-734 | Afuco™ Anti-TFPI ADCC Recombinant Antibody (Concizumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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