Afuco™ Anti-TGFB2 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-100)
CAT#: AFC-TAB-100
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to TGF beta 2. It is a human monoclonal antibody and an immunosuppressive drug developed to reduce scarring after glaucoma drainage surgery.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line EFO-21
Immunofluorescent staining of human cell line EFO-21 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6134/2063_C8_2_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (EFO-21, hTERT-RPE1, U-2 OS)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000092969-TGFB2
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Specifications
- Immunogen
- An epitope of TGF beta 2 (Human).
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- ELISA, IP, FC, FuncS, Neut, IF
- Conjugate
- Unconjugated
- Trade name
- Trabio
- Generic Name
- Lerdelimumab
- Related Disease
- Glaucoma surgery
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Biosimilar Overview
Please refer to Lerdelimumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Lerdelimumab.
Related Diseases
Inflammatory Bowel Diseases
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Lerdelimumab"
DrugMonitor™ Anti-Lerdelimumab Antibody (VS-1224-YC656)Lerdelimumab is a human monoclonal antibody and immunosuppressant targeting TGF beta 2, with potential for treating fibrosis, cataract, retinopathy, and connective tissue disease. The DrugMonitor™ Anti-Lerdelimumab Antibody (VS-1224-YC656) is an anti-drug antibody (ADA) against Lerdelimumab. This drug-based antibody is raised in mice immunized with the Lerdelimumab. The anti-Lerdelimumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Lerdelimumab in samples.
See other products for "TGFB2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1494z-S(P) | Recombinant Anti-Human TGFB2 Antibody scFv Fragment | ELISA, WB, IF, FuncS | scFv |
| HPAB-M0662-YC-S(P) | Human Anti-TGFB2 Recombinant Antibody; scFv Fragment (HPAB-M0662-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-M0663-YC-S(P) | Human Anti-TGFB2 Recombinant Antibody; scFv Fragment (HPAB-M0663-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-0665YY-S(P) | Human Anti-TGFB2 Recombinant Antibody (clone GDF11 Inh-2); scFv Fragment | Inhib, ELISA, WB | Human scFv |
| HPAB-2108-FY-S(P) | Human Anti-TGFB2 Recombinant Antibody (clone 6A5); scFv Fragment | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-100 | Anti-Human TGF beta 2 Recombinant Antibody (TAB-100) | ELISA, IP, FC, FuncS, Neut, IF, ICC | IgG4 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2017CQ | Rat Anti-Tgfb2 Recombinant Antibody (clone CBL883) | IHC, Neut, WB | Rat IgG2 |
| NEUT-2018CQ | Rat Anti-Tgfb2 Recombinant Antibody (clone CBL649) | Neut | Rat IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0664-YC | Human Anti-TGFB2 Recombinant Antibody (HPAB-M0664-YC) | ELISA, FuncS | Human IgG |
| HPAB-M0665-YC | Human Anti-TGFB2 Recombinant Antibody (HPAB-M0665-YC) | ELISA, FuncS | Human IgG |
| HPAB-M0666-YC | Human Anti-TGFB2 Recombinant Antibody (HPAB-M0666-YC) | ELISA, FuncS | Human IgG |
| HPAB-M0667-YC | Human Anti-TGFB2 Recombinant Antibody (HPAB-M0667-YC) | ELISA, FuncS | Human IgG |
| HPAB-2108-FY | Human Anti-TGFB2 Recombinant Antibody (clone 6A5) | ELISA | Human IgG4 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0662-YC-F(E) | Human Anti-TGFB2 Recombinant Antibody; Fab Fragment (HPAB-M0662-YC-F(E)) | ELISA, FuncS | Human Fab |
| HPAB-M0663-YC-F(E) | Human Anti-TGFB2 Recombinant Antibody; Fab Fragment (HPAB-M0663-YC-F(E)) | ELISA, FuncS | Human Fab |
| HPAB-M0664-YC-F(E) | Human Anti-TGFB2 Recombinant Antibody; Fab Fragment (HPAB-M0664-YC-F(E)) | ELISA, FuncS | Human Fab |
| HPAB-0665YY-F(E) | Human Anti-TGFB2 Recombinant Antibody (clone GDF11 Inh-2); Fab Fragment | Inhib, ELISA, WB | Human Fab |
| HPAB-2108-FY-F(E) | Human Anti-TGFB2 Recombinant Antibody (clone 6A5); Fab Fragment | ELISA | Human Fab4 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY188 | Mouse Anti-TGFB2 (clone 6A5) scFv-Fc Chimera | Neut, ELISA | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2277 | Anti-TGFB2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7211 | Anti-Mouse TGFB2 Immunohistochemistry Kit | IHC |
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