Anti-TIMP3 (clone W24V131) Recombinant Antibody Coupled Liposome (VS-1024-FY133) (CAT#: VS-1024-FY133)

• Potential Clinical Applications
• Glioma

• Clone
• W24V131

• Antibody Type
• IgG

• Antibody Host
• Mouse

• Antibody Reactivity
• Human

• Antibody Description
• This is a recombinant mouse monoclonal antibody specifically designed to bind to human Tissue Inhibitor of Metalloproteinases 3 (TIMP3). TIMP3 is a protein with important biological functions, playing a key role in regulating matrix metalloproteinase activity and extracellular matrix remodeling. The high specificity and sensitivity of this antibody make it a powerful tool for studying TIMP3 and its associated biological processes, providing new research directions for the diagnosis and treatment of related diseases.

• Storage
• See in the COA

• Storage Shelf Time
• See in the COA

• Target
• TIMP3

• Alternative Names
• TIMP3; Human TIMP3

• Full Name
• TIMP Metallopeptidase Inhibitor 3

• Gene ID
• 7078

• UniProt ID
• P35625

• Sequence Similarities
• Belongs to the protease inhibitor I35 (TIMP) family.

• Cellular Localization
• Secreted

• Post Translation Modifications
• Modification sites at PhosphoSitePlus ( P35625 )
  Modification sites at neXtProt ( NX_P35625 )
  Glycosylation from GlyGen (P35625) 1 site, 11 N-linked glycans (1 site)

• Protein Refseq
• NP_000353.1

• Function
• Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
  May form part of a tissue-specific acute response to remodeling stimuli.
  Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.

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