Rabbit Anti-TJP3 Recombinant Antibody (VS13-YC1160) (CAT#: VS13-YC1160)
The Rabbit Anti-TJP3 Recombinant Antibody is specific for human and rat TJP3. TJP3 encodes a MAGUK family protein linking cytoskeletons and tight junctions, regulating junction components like cyclin D1, with several transcript versions. The anti-TJP3 antibody can be used for Western blot (1/500-1/1000).
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46863/1137_C4_4_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46863/1137_C4_4_selected.jpg
Figure 2 IF staining of human cell line CACO-2
(Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53337/if_selected.jpg
(Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53337/if_selected.jpg
Figure 3 Small intestine
(High expression in small intestine)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53337/141944_A_5_2_val_selected.jpg
(High expression in small intestine)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53337/141944_A_5_2_val_selected.jpg
Figure 4 Duodenum.
(High expression in duodenum)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13244/29828_A_7_2_val_selected.jpg
(High expression in duodenum)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13244/29828_A_7_2_val_selected.jpg
Figure 5 Testis
(Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Round or early spermatids Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53337/141944_A_6_6.jpg
(Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Round or early spermatids Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53337/141944_A_6_6.jpg
Figure 6 Fallopian tube
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53337/141944_A_8_7.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53337/141944_A_8_7.jpg
Figure 7 Lymph node
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53337/141944_A_8_8.jpg
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/53337/141944_A_8_8.jpg
Figure 8 RNA cell line category: Cell line enhanced (BEWO, CAPAN-2, MCF7, OE19, SK-BR-3, T-47d)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105289-TJP3
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105289-TJP3
Specifications
- Immunogen
- Recombinant human Zonula occludens protein 3.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Rat TJP3
- Species Reactivity
- Human, Rat
- Applications
- WB
- Conjugate
- NONE
- Related Disease
- Celiac Disease
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Target
- Alternative Names
- Tight Junction Protein 3; Zonula Occludens Protein 3; Zona Occludens Protein 3; ZO3; Tight Junction Protein 3 (Zona Occludens 3); Tight Junction Protein ZO-3; Zona Occludens 3; ZO-3;
- Gene ID
- 27134
- UniProt ID
- O95049
- Long Name
- Tight Junction Protein 3
- Sequence Similarities
- Belongs to the MAGUK family.
- Cellular Localization
- Cell junction; Cell membrane; Membrane; Nucleus; Tight junction
- Protein Refseq
- XP_047294567.1; XP_054176526.1; NP_001254489.1; NP_001254490.1
- Function
- TJP1, TJP2, and TJP3 are closely related scaffolding proteins that link tight junction (TJ) transmembrane proteins such as claudins, junctional adhesion molecules, and occludin to the actin cytoskeleton.
The tight junction acts to limit movement of substances through the paracellular space and as a boundary between the compositionally distinct apical and basolateral plasma membrane domains of epithelial and endothelial cells. Binds and recruits PATJ to tight junctions where it connects and stabilizes apical and lateral components of tight junctions.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "TJP3"
Select a product category from the dropdown menu below to view related products.
Please select product type
Rabbit Monoclonal Antibody Products
IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3578 | Rabbit Anti-TJP3 Recombinant Antibody (clone DS3578AB) | WB, ICC, IF | Rabbit IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS13-YC1160. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
Application: ELISA, FC, IP, FuncS, IF, Neut, WB
Application: WB, ELISA, Neut, FuncS
Application: Neut, FC, IHC-Fr, IP, BA
Application: WB, ELISA, FC, IHC, IF, IP
Application: FC, IA, IF, IP, IHC, FuncS
-1.png)
Application: ELISA
Application: ELISA, Inhib, FC, Neut
-1.jpg)
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
