Afuco™ Anti-TNC ADCC Recombinant Antibody (Tenatumomab), ADCC Enhanced (CAT#: AFC-TAB-877)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant humanized (from mouse) antibody expressed in CHO binding to human Tenascin C/TNC. Tenatumomab is a monoclonal antibody designed for the treatment of cancer.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Neuropil
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4592/12212_B_7_5.jpg
(Neuropil
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4592/12212_B_7_5.jpg
Figure 2 Kidney
(Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4823/13810_A_8_5.jpg
(Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4823/13810_A_8_5.jpg
Figure 3 Testis
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4592/12212_A_5_6.jpg
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4592/12212_A_5_6.jpg
Figure 4 RNA cell line category: Cell line enhanced (BJ hTERT+, hTEC/SVTERT24-B, U-138 MG, U-251 MG, U-87 MG, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000041982-TNC
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000041982-TNC
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Clone
- Tenatumomab
- Applications
- FC, IP, ELISA, Neut, FuncS, IF
- Conjugate
- Unconjugated
- Generic Name
- Tenatumomab
- Related Disease
- Cancers
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Tenatumomab; ST2146; TNC; tenascin C; hexabrachion (tenascin C, cytotactin), HXB; tenascin; hexabrachion (tenascin); MGC167029; TN; GP 150-225; cytotactin; neuronectin; myotendinous antigen; tenascin-C isoform 14/AD1/16; glioma-associated-extracellular matrix antigen;
- Gene ID
- 3371
- UniProt ID
- P24821
Related Resources
Please refer to Tenatumomab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Tenatumomab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Tenatumomab"
Anti-Human Tenascin C/TNC Recombinant Antibody (Tenatumomab)Recombinant humanized (from mouse) antibody expressed in CHO binding to human Tenascin C/TNC. Tenatumomab is a monoclonal antibody designed for the treatment of cancer.
See other products for "Tnc"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1379z | Mouse Anti-TNC Recombinant Antibody (clone 22B10) | WB, IP, IF, IHC, ELISA | Mouse IgG1 |
| HPAB-0320CQ | Mouse Anti-TNC Recombinant Antibody (HPAB-0320CQ) | ELISA, WB, FuncS | Mouse IgG1, κ |
| MRO-1481-CN | Rabbit Anti-TNC Recombinant Antibody (clone CBACN-550) | WB, IHC, FC | Rabbit IgG |
| HPAB-M0678-YC | Mouse Anti-TNC Recombinant Antibody (HPAB-M0678-YC) | ELISA, SPR, IHC | Mouse IgG |
| HPAB-0190-WJ | Human Anti-TNC Recombinant Antibody (HPAB-0190-WJ) | ELISA | Human IgE |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-877 | Anti-Human Tenascin C/TNC Recombinant Antibody (Tenatumomab) | IHC | IgG2b |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-587CT | Human Anti-TNC Recombinant Antibody (TAB-587CT) | ELISA, FC | Human lgG4 |
| TAB-588CT | Human Anti-TNC Recombinant Antibody (TAB-588CT) | ELISA, FC | Human lgG4 |
| TAB-589CT | Human Anti-TNC Recombinant Antibody (TAB-589CT) | ELISA, FC | Human lgG4 |
| TAB-590CT | Human Anti-TNC Recombinant Antibody (TAB-590CT) | ELISA, FC | Human lgG4 |
| TAB-591CT | Anti-Human Tenascin C Recombinant Antibody (2B10) | ELISA, IF | Human antibody |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0810MZ | Chicken Anti-Tenascin C Polyclonal IgY | WB | Chicken antibody |
| BRD-0910MZ | Chicken Anti-Tenascin C Polyclonal IgY | WB | Chicken antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2050CQ | Rat Anti-TNC Recombinant Antibody (clone CBL402) | WB, ICC, Neut | Rat IgG2a |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3601 | Rabbit Anti-TNC Recombinant Antibody (clone DS3601AB) | WB, IHC, ICC | Rabbit IgG |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC2108 | PE-B*07:02/Human TNC (IATVDSYVI) MHC Tetramer | FCM | |
| MHC-LC2109 | APC-B*07:02/Human TNC (IATVDSYVI) MHC Tetramer | FCM |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0441-YC-S(P) | Mouse Anti-TNC Recombinant Antibody (clone ST2146); scFv Fragment | ELISA, WB, FC | Mouse scFv |
| HPAB-0443-YC-S(P) | Human Anti-TNC Recombinant Antibody; scFv Fragment (HPAB-0443-YC-S(P)) | ELISA, IHC | Human scFv |
| HPAB-0444-YC-S(P) | Human Anti-TNC Recombinant Antibody; scFv Fragment (HPAB-0444-YC-S(P)) | ELISA, IHC | Human scFv |
| HPAB-N0264-YC-S(P) | Human Anti-TNC Recombinant Antibody; scFv Fragment (HPAB-N0264-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-N0265-YC-S(P) | Human Anti-TNC Recombinant Antibody; scFv Fragment (HPAB-N0265-YC-S(P)) | ELISA | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0320CQ-F(E) | Mouse Anti-TNC Recombinant Antibody; Fab Fragment (HPAB-0320CQ-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-M0678-YC-F(E) | Mouse Anti-TNC Recombinant Antibody; Fab Fragment (HPAB-M0678-YC-F(E)) | ELISA | Mouse Fab |
| HPAB-AP203-YC-F(E) | Mouse Anti-TNC Recombinant Antibody; Fab Fragment (HPAB-AP203-YC-F(E)) | ELISA, FuncS | Mouse Fab |
| HPAB-N0264-YC-F(E) | Human Anti-TNC Recombinant Antibody; Fab Fragment (HPAB-N0264-YC-F(E)) | ELISA, FuncS | Human Fab |
| HPAB-N0265-YC-F(E) | Human Anti-TNC Recombinant Antibody; Fab Fragment (HPAB-N0265-YC-F(E)) | ELISA | Human Fab |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NBD-0083-YJ-VHH | Camelid Anti-TNC Recombinant Single Domain Antibody (NJT3) | ELISA, IF | Camelid VHH |
| NBD-0084-YJ-VHH | Camelid Anti-TNC Recombinant Single Domain Antibody (NJT4) | ELISA, IF, In vivo imaging | Camelid VHH |
| NBD-0085-YJ-VHH | Camelid Anti-TNC Recombinant Single Domain Antibody (NJT6) | ELISA, IF, In vivo imaging | Camelid VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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