Afuco™ Anti-TNF ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-006) (CAT#: AFC-TAB-006)

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to Human TNF. It is a monoclonal antibody against tumour necrosis factor alpha (TNF-α) used to treat autoimmune diseases.

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Custom Production

We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

Sequences:
Isotype :
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Endotoxin :
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Other Requirements:
We require custom production
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • rhTNF emulsified with complete Fraud`s adjuvant.
  • Host Species
  • Chimeric
  • Derivation
  • Chimeric (mouse/human)
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Applications
  • IF, IP, Neut, FuncS, ELISA, FC
  • Conjugate
  • Unconjugated
  • Trade name
  • Remicade, Remsima, Inflectra
  • Generic Name
  • Infliximab
  • Related Disease
  • Ankylosing spondylitis (AS)

Product Property

  • Purity
  • >95% by SDS-PAGE
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • TNF; tumor necrosis factor; TNFA, tumor necrosis factor (TNF superfamily, member 2); DIF; TNF superfamily; member 2; TNF alpha; TNFSF2; TNF-a; cachectin; APC1 protein; TNF, monocyte-derived

Related Resources

  • Biosimilar Overview
  • Related Diseases
  • Related Signaling Pathways
Please refer to Infliximab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Infliximab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Infliximab"

Anti-Human TNF Recombinant Antibody (Infliximab)
Recombinant monoclonal antibody to Human TNF. Infliximab (INN; trade name Remicade) is a monoclonal antibody against tumour necrosis factor alpha (TNF-α) used to treat autoimmune diseases.
Infliximab was approved for the treatment of psoriasis, Crohn's disease, ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis, and ulcerative colitis.
DrugMonitor™ Anti-Infliximab Antibody (VS-1224-YC603)
Infliximab is a chimeric monoclonal IgG1 antibody targeting tumor necrosis factor-alpha (TNF-α), composed of human constant (75%) and murine variable (25%) regions, approved for intravenous treatment of various inflammatory disorders. The DrugMonitor™ Anti-Infliximab Antibody (VS-1224-YC603) is an anti-drug antibody (ADA) against Infliximab. This drug-based antibody is raised in mice immunized with the Infliximab. The anti-Infliximab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Infliximab in samples.

See other products for "TNF"

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