Human Anti-TNFRSF10B Recombinant Antibody (clone TRA-8) (CAT#: HPAB-1180WJ)
This product is a humanized antibody targeting human DR5. This antibody can be used for the treatment of apoptosis-related disease and treatment of dysregulated cell growth.
Specific Inquiry
ELISA
Figure 7 Show binding activity of soluble TRAIL and TRA-8 to DR5 and DR4.
ELISA plates were coated with DR5/hIgG1 or DR4/hIgG1 and then incubated with TRAIL or TRA-8.
ELISA
Figure 8 Soluble TRAIL and TRA-8 bind to DR5 and DR4.
ELISA plates were coated with DR5/hIgG1 or DR4/hIgG1 and then incubated with TRAIL or TRA-8.
FC
Figure 9 Shows Flow cytometry analysis of the surface expression of DR5.
FC
Figure 10 T cell lines were incubated with TRA-8 or murine IgG1 isotype control antibody followed by PE-conjugated goat anti-mouse IgG1.
Specifications
- Immunogen
- Recombinant human DR5 protein
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG
- Specificity
- Human DR5
- Species Reactivity
- Human
- Clone
- TRA-8
- Applications
- Cyt, IF, Inhib, WB, ELISA, FC
- Related Disease
- Apoptosis-related disease
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The TNFRSF10B antibody has been reported in applications of Cytotoxicity, Immunofluorescence, Inhibition, Western Blot, Enzyme-linked Immunosorbent Assay, Flow Cytometry.
Cyt: 0-1000 ng/ml.
Inhib: 200 μg.
Target
- Alternative Names
- DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5
- Gene ID
- 8795
- UniProt ID
- O14763
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Single Domain Antibody Products
Humanized Antibody Products
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Mouse Antibody Products
Rabbit Monoclonal Antibody Products
Agonistic Antibody Products
Fab Antibody Products
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ADCC Enhanced Antibody Products
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-052 | Recombinant Anti-human TNFRSF10B VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
| HPAB-0703-YJ-VHH | Camelid Anti-TNFRSF10B Recombinant Single Domain Antibody (HPAB-0703-YJ-VHH) | ELISA, Apop | Camelid VHH |
| HPAB-0704-YJ-VHH | Camelid Anti-TNFRSF10B Recombinant Single Domain Antibody (HPAB-0704-YJ-VHH) | ELISA | Camelid VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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