Human Anti-TNFRSF17 Recombinant Antibody (clone hSG16.17) (CAT#: HPAB-M0233-YC)
Provided is a humanized antibody hSG16.17 that specifically binds to BCMA. The antibody is useful for treatment studies of various cancers and immune disorders as well as detecting BCMA.
Specific Inquiry
Inhib
Figure 1 shows inhibiton of APRIL blocking titrated with anti-BCMA antibodies.
FuncS
Figure 2 show in vivo activity of multi dosed hSG16.17-SEA in MM1S disseminated tumor model in SCID mice.
FuncS
Figure 3 provides ADCC activity of the SG16.17 SEA antibody on MM1R target cells.
ELISA
Figure 4 shows competition binding assay showing binding of chimeric SG16.17 to human FcRIIIa.
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG
- Specificity
- Human TNFRSF17
- Species Reactivity
- Human
- Clone
- hSG16.17
- Applications
- Inhib, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Inhibition and Functional Assay.
Target
- Alternative Names
- TNF Receptor Superfamily Member 17; B-Cell Maturation Protein; BCMA; BCM; Tumor Necrosis Factor Receptor Superfamily, Member 17; Tumor Necrosis Factor Receptor Superfamily Member 17;
- Gene ID
- 608
- UniProt ID
- Q02223
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone hSG16.17"
See other products for "TNFRSF17"
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-019 | Mouse Anti-TNFRSF17 Recombinant Antibody (clone J22.9-xi); scFv Fragment | Neut, FuncS | Mouse scFv |
| HPAB-1875LY-S(P) | Human Anti-TNFRSF17 Recombinant Antibody; scFv Fragment (HPAB-1875LY-S(P)) | ELISA | Human scFv |
| HPAB-0560-FY-S(P) | Human Anti-TNFRSF17 Recombinant Antibody; scFv Fragment (HPAB-0560-FY-S(P)) | FuncS, FC, ELISA | Humanized scFv |
| HPAB-0561-FY-S(P) | Human Anti-TNFRSF17 Recombinant Antibody; scFv Fragment (HPAB-0561-FY-S(P)) | FuncS, FC, ELISA | Humanized scFv |
| HPAB-0562-FY-S(P) | Human Anti-TNFRSF17 Recombinant Antibody; scFv Fragment (HPAB-0562-FY-S(P)) | FC | Human scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1220CL | Human Anti-TNFRSF17 Recombinant Antibody (TAB-1220CL) | ELISA, Cyt, FC | Humanized antibody |
| TAB-1230CL | Human Anti-TNFRSF17 Recombinant Antibody (TAB-1230CL) | ELISA | Humanized IgG |
| TAB-1231CL | Human Anti-TNFRSF17 Recombinant Antibody (TAB-1231CL) | ELISA | Humanized IgG |
| TAB-1232CL | Human Anti-TNFRSF17 Recombinant Antibody (TAB-1232CL) | ELISA | Humanized IgG |
| TAB-1220CL-F(E) | Human Anti-TNFRSF17 Recombinant Antibody; Fab Fragment (TAB-1220CL-F(E)) | ELISA | Humanized Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1221CL | Anti-Human TNFRSF17 Recombinant Antibody (TBL-CLN1) | Cyt | |
| TAB-1222CL | Mouse Anti-TNFRSF17 Recombinant Antibody (TAB-1222CL) | FC | Mouse IgG1 |
| TAB-1223CL | Mouse Anti-TNFRSF17 Recombinant Antibody (TAB-1223CL) | FC | Mouse IgG1 |
| TAB-1224CL | Mouse Anti-TNFRSF17 Recombinant Antibody (TAB-1224CL) | FC | Mouse IgG1 |
| TAB-1225CL | Mouse Anti-TNFRSF17 Recombinant Antibody (TAB-1225CL) | FC | Mouse IgG2b |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1214CL-S(P) | Human Anti-TNFRSF17 Recombinant Antibody; scFv Fragment (TAB-1214CL-S(P)) | ELISA, FC | Human scFv |
| TAB-1215CL-S(P) | Human Anti-TNFRSF17 Recombinant Antibody; scFv Fragment (TAB-1215CL-S(P)) | ELISA | Human scFv |
| TAB-1216CL-S(P) | Human Anti-TNFRSF17 Recombinant Antibody; scFv Fragment (TAB-1216CL-S(P)) | ELISA | Human scFv |
| TAB-1217CL-S(P) | Human Anti-TNFRSF17 Recombinant Antibody; scFv Fragment (TAB-1217CL-S(P)) | ELISA, FC | Human scFv |
| TAB-1208CL-F(E) | Human Anti-TNFRSF17 Recombinant Antibody; Fab Fragment (TAB-1208CL-F(E)) | ELISA, FC | Human Fab |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1219CL-S(P) | Human Anti-TNFRSF17 Recombinant Antibody; scFv Fragment (TAB-1219CL-S(P)) | ELISA, FC, Block, FuncS | Human scFv |
| TAB-1226CL-F(E) | Human Anti-TNFRSF17 Recombinant Antibody; Fab Fragment (TAB-1226CL-F(E)) | FuncS | Chimeric (mouse/human) Fab |
| TAB-1227CL-F(E) | Human Anti-TNFRSF17 Recombinant Antibody; Fab Fragment (TAB-1227CL-F(E)) | FuncS | Chimeric (mouse/human) Fab |
| TAB-1228CL-F(E) | Human Anti-TNFRSF17 Recombinant Antibody; Fab Fragment (TAB-1228CL-F(E)) | FuncS | Chimeric (mouse/human) Fab |
| TAB-1229CL-F(E) | Human Anti-TNFRSF17 Recombinant Antibody; Fab Fragment (TAB-1229CL-F(E)) | FuncS | Chimeric (mouse/human) Fab |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2125CQ | Rat Anti-TNFRSF17 Recombinant Antibody (clone 3D44) | Neut, WB | Rat IgG2 |
| NEUT-2126CQ | Rat Anti-TNFRSF17 Recombinant Antibody (clone Vicky-1) | WB, Neut, ELISA, FC, ICC, IF, IHC | Rat IgG1 |
| NEUT-2128CQ | Rat Anti-Tnfrsf17 Recombinant Antibody (clone 17B1) | Neut, WB | Rat IgG2 |
| NEUT-2131CQ | Rat Anti-Tnfrsf17 Recombinant Antibody (clone Vicky-2) | WB, Neut, FC, IP | Rat IgG2a |
| NEUT-2132CQ | Rat Anti-Tnfrsf17 Recombinant Antibody (clone CBL183) | Neut, WB | Rat IgG2 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2127CQ | Rat Anti-TNFRSF17 Recombinant Antibody (clone CBL370) | WB, Block | Rat IgG2a |
| NEUT-2129CQ | Rat Anti-Tnfrsf17 Recombinant Antibody (clone CBL336) | Block, WB | Rat IgG2a |
| NEUT-2130CQ | Mouse Anti-Tnfrsf17 Recombinant Antibody (clone CBL337) | Block | Mouse IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0009-DJB-F(E) | Mouse Anti-TNFRSF17 Recombinant Antibody (clone CA8); Fab Fragment | ELISA, Neut | Mouse Fab |
| HPAB-0010-DJB-F(E) | Human Anti-TNFRSF17 Recombinant Antibody; Fab Fragment (HPAB-0010-DJB-F(E)) | ELISA, Neut | Humanized Fab |
| HPAB-0011-DJB-F(E) | Mouse Anti-TNFRSF17 Recombinant Antibody; Fab Fragment (HPAB-0011-DJB-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0012-DJB-F(E) | Human Anti-TNFRSF17 Recombinant Antibody; Fab Fragment (HPAB-0012-DJB-F(E)) | ELISA, FC | Chimeric (Mouse/Human) Fab |
| HPAB-0013-DJB-F(E) | Human Anti-TNFRSF17 Recombinant Antibody; Fab Fragment (HPAB-0013-DJB-F(E)) | ELISA, FC | Chimeric (Mouse/Human) Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-021LC | Human Anti-TNFRSF17 Recombinant Antibody (clone J6M0) | ELISA, FuncS | Humanized IgG1, κ |
| HPAB-1334LY | Human Anti-TNFRSF17 Recombinant Antibody (HPAB-1334LY) | SPR, ELISA, HTRF, FC | Human IgG2 |
| HPAB-1335LY | Human Anti-TNFRSF17 Recombinant Antibody (HPAB-1335LY) | ELISA, RIA | Human IgG2 |
| HPAB-1336LY | Human Anti-TNFRSF17 Recombinant Antibody (HPAB-1336LY) | ELISA, RIA | Human IgG2 |
| HPAB-1337LY | Human Anti-TNFRSF17 Recombinant Antibody (HPAB-1337LY) | ELISA, RIA | Human IgG2 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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