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  • Anti-TNFRSF1B Recombinant Antibody (VS-0824-YJ45)

Anti-TNFRSF1B Recombinant Antibody (VS-0824-YJ45) (CAT#: VS-0824-YJ45)

Clone 70 is a mouse IgG2a that binds to an extracellular domain of the C-terminal cysteine loop of the p75 TNF receptor. It may cause a decrease in the rate of TNT dissociation from the receptors. Clone ch32 is a human IgG1 binding to aa 163-179 of human TBP-II. It can inhibit TNF function in this cell without having any inhibitor effect on TNF binding. It has a potential to cause a decrease in the rate of TNT dissociation from the receptors

Sub Cat Clone Host Applications Type Size Conjugation Endotoxin Purity Fc Engineering  
VS-0824-YJ27 70 Mouse ELISA, WB Mouse IgG2a kappa
VS-0824-YJ28 ch32 Human ELISA, WB, Inhib Chimeric (mouse/human) IgG1 kappa
More Infomation
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Normal Tissue
Figure 1 IHC staining of human stomach
Figure 1 IHC staining of human stomach
(Immunohistochemical staining of human stomach shows positivity in plasma.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4796/ihc_selected.jpg
Figure 2 Cerebral cortex
Figure 2 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4796/14125_B_8_5.jpg
Figure 3 Colon
Figure 3 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4796/13963_A_9_3.jpg
Figure 4 Liver
Figure 4 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4796/13963_A_8_4.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4796/13963_A_8_5.jpg
Figure 6 Testis
Figure 6 Testis
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4796/13963_A_6_6.jpg
Figure 7 Lymph node
Figure 7 Lymph node
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4796/13963_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (CAPAN-2, K-562, THP-1, U-87 MG, U-937)
Figure 8 RNA cell line category: Cell line enhanced (CAPAN-2, K-562, THP-1, U-87 MG, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000028137-TNFRSF1B

Specifications

  • Immunogen
  • Purified TBP-II
  • Specificity
  • Human TNFRSF1B
  • Species Reactivity
  • Human
  • Related Disease
  • Tumor

Product Property

  • Purity
  • >95% as determined by SDS-PAGE or SEC-HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • p75; TBPII; TNFBR; TNFR2; CD120b; TNFR1B; TNFR80; TNF-R75; p75TNFR; TNF-R-II; tumor necrosis factor receptor superfamily member 1B; TNF-R2; TNF-RII; p75 TNF receptor; p80 TNF-alpha receptor; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; tumor necrosis factor receptor 2; tumor necrosis factor receptor type II

Recommended Products

Secondary Antibody

Isotype Control

Recommended Dilution Buffer

Reconstitution Buffer

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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CAT Product Name Application Type
MOB-2054z Mouse Anti-TNFRSF1B Recombinant Antibody (clone 33A8) WB, ELISA, Neut Mouse IgG1
MOB-1590MZ Recombinant Mouse Anti-Human TNFRSF1B Antibody (clone 33332.422) ELISA, Neut, WB Mouse antibody
MOR-0014-FY Mouse Anti-TNFRSF1B Recombinant Antibody (clone MR2-1) FC, FuncS, IA, IF, IP, WB Mouse IgG1
MOR-0018-FY Mouse Anti-TNFRSF1B Recombinant Antibody (clone 80M2) FC, FuncS, IA, IF, IP Mouse IgG1
HPAB-1550WJ Mouse Anti-TNFRSF1B Recombinant Antibody (clone 32) ELISA, WB Mouse IgG1

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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