Afuco™ Anti-TNFSF13B ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-030) (CAT#: AFC-TAB-030)

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to Human BLyS. It is a human monoclonal antibody that inhibits B-cell activating factor (BAFF), also known as B-lymphocyte stimulator (BLyS). B cells are responsible for part of the normal immune response, and also for the over-aggressive immune response in autoimmune diseases like systemic lupus erythematosus (SLE).

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Formats:
  • Isotype Switching:
  • Fc Engineering:
  • Modalities:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Applications
  • FC, IP, ELISA, Neut, FuncS, IF
  • Conjugate
  • Unconjugated
  • Trade name
  • Benlysta
  • Generic Name
  • Belimumab
  • Related Disease
  • Systemic lupus erythematosus (SLE)

Product Property

  • Purity
  • >95% by SDS-PAGE
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • TNFSF13B; tumor necrosis factor (ligand) superfamily, member 13b; TNFSF20; tumor necrosis factor ligand superfamily member 13B; BAFF; BLYS; CD257; TALL 1; TALL1; THANK

Related Resources

  • Biosimilar Overview
Please refer to Belimumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Belimumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Belimumab"

DrugMonitor™ Anti-Belimumab Antibody (VS-1224-YC177)
Belimumab is a fully human recombinant IgG1 lambda monoclonal antibody inhibiting soluble human BLyS, first approved for systemic lupus erythematosus (SLE) and lupus nephritis treatment. The DrugMonitor™ Anti-Belimumab Antibody (VS-1224-YC177) is an anti-drug antibody (ADA) against Belimumab. This drug-based antibody is raised in mice immunized with the Belimumab. The anti-Belimumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Belimumab in samples.

See other products for "TNFSF13B"

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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