Human Anti-TNFSF14 Recombinant Antibody (clone h18B1) (CAT#: HPAB-0850-CN)
This is a humanized antibody derived from murine antibody 18B1, which specifically binds the LIGHT polypeptide. Antibody h18B1 can be used in the treatment or diagnosis of immune, inflammatory and malignant diseases or conditions.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line THP-1
(Immunofluorescent staining of human cell line THP-1 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12700/2061_E6_3_selected.jpg
(Immunofluorescent staining of human cell line THP-1 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12700/2061_E6_3_selected.jpg
Figure 2 IHC staining of human urinary bladder
(Immunohistochemical staining of human urinary bladder shows strong cytoplasmic positivity in umbrella cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12700/ihc_selected.jpg
(Immunohistochemical staining of human urinary bladder shows strong cytoplasmic positivity in umbrella cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12700/ihc_selected.jpg
Figure 3 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12700/57480_A_9_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12700/57480_A_9_3.jpg
Figure 4 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12700/57480_A_9_4.jpg
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12700/57480_A_9_4.jpg
Figure 5 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12700/57480_A_8_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12700/57480_A_8_5.jpg
Figure 6 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12700/57480_A_4_6.jpg
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12700/57480_A_4_6.jpg
Figure 7 RNA cell line category: Cell line enhanced (HDLM-2, NB-4, THP-1, U-937)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000125735-TNFSF14
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000125735-TNFSF14
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG1, κ
- Specificity
- Human TNFSF14
- Species Reactivity
- Human
- Clone
- h18B1
- Applications
- ELISA, FC
- Related Disease
- Immune, inflammatory, malignant diseases or conditions
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- TNF Superfamily Member 14; Tumor Necrosis Factor (Ligand) Superfamily, Member 14; Herpesvirus Entry Mediator Ligand; HVEML; LIGHT; Tumor Necrosis Factor Ligand Superfamily Member 14; Tumor Necrosis Factor Superfamily Member 14;
- Gene ID
- 8740
- UniProt ID
- O43557
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Please select product type
IgG Antibody Products
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Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3612z | Mouse Anti-TNFSF14 Recombinant Antibody (clone 19G4) | WB, IP, IF, IHC, ELISA | Mouse IgG2a, κ |
| MOB-1093CT | Recombinant Mouse anti-Human TNFSF14 Monoclonal antibody (EML2020) | IHC-P, WB | |
| HPAB-J0293-YC | Mouse Anti-TNFSF14 Recombinant Antibody (clone m10D11) | Inhib, Block | Mouse IgG |
| HPAB-J0294-YC | Mouse Anti-TNFSF14 Recombinant Antibody (clone m5E10) | ELISA, FC, Inhib | Mouse IgG |
| HPAB-J0295-YC | Mouse Anti-TNFSF14 Recombinant Antibody (clone m13C7) | Inhib, FC | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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