Mouse Anti-TNFSF14 Recombinant Antibody (VS3-FY2770)
CAT#: VS3-FY2770
This anti-TNFSF14 antibody is a mouse recombinant monoclonal antibody that is created to attach to CD258 protein, a calculated weight of 26.4 kDa. It shows capability of cross-reacting with human and mouse. The monoclonal antibody can be used in the area of Rheumatoid Arthritis and Inflammatory Bowel Disease. This monoclonal antibody can be used in Western Blot, Immunohistochemistry, Flow cytometry, ELISA.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line THP-1
Immunofluorescent staining of human cell line THP-1 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12700/2061_E6_3_selected.jpg
Normal Tissue
Figure 2 IHC staining of human urinary bladder
Immunohistochemical staining of human urinary bladder shows strong cytoplasmic positivity in umbrella cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12700/ihc_selected.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12700/57480_A_9_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12700/57480_A_9_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12700/57480_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12700/57480_A_4_6.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (HDLM-2, NB-4, THP-1, U-937)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000125735-TNFSF14
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Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- TNF superfamily member 14 of human and mouse origins
- Species Reactivity
- Human, Mouse
- Applications
- WB, IHC, FC, ELISA
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 26.4 kDa.
- Related Disease
- Rheumatoid Arthritis and Inflammatory Bowel Disease
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/2000
Immunohistochemistry: 1/50-1/200
Flow cytometry: 1/50-1/200
ELISA: 1/1000-1/10000
Target
- Alternative Names
- TNF Superfamily Member 14; Tumor Necrosis Factor (Ligand) Superfamily, Member 14; Herpesvirus Entry Mediator Ligand; HVEML; LIGHT; Tumor Necrosis Factor Ligand Superfamily Member 14; Tumor Necrosis Factor Superfamily Member 14
- Gene ID
- 8740
- Sequence Similarities
- Belongs to the tumor necrosis factor family.
- Cellular Localization
- Cytoplasm
- Post Translation Modifications
- N-glycosylated.
The soluble form of isoform 1 derives from the membrane form by proteolytic processing.
Glycosylation at Asn102
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 1 site
- Protein Refseq
- NP_001363816.1; NP_003798.2; NP_742011.2
- Function
- Acts as a ligand for TNFRSF14/HVEM (PubMed:9462508, 10754304).
Upon binding to TNFRSF14/HVEM, delivers costimulatory signals to T cells, leading to T cell proliferation and IFNG production.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "TNFSF14"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-159CQ | Anti-Human TNFSF14 Recombinant Antibody (TR01G03) | ELISA, FC, WB | Human antibody |
| TAB-159CQ-S(P) | Anti-Human TNFSF14 Recombinant Antibody scFv Fragment (TR01G03) | ELISA, FC, WB | Human antibody |
| TAB-159CQ-F(E) | Anti-Human TNFSF14 Recombinant Antibody Fab Fragment (TR01G03) | ELISA, FC, WB | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1093CT | Recombinant Mouse anti-Human TNFSF14 Monoclonal antibody (EML2020) | IHC-P, WB | |
| HPAB-0847-CN | Human Anti-TNFSF14 Recombinant Antibody (clone h5E10) | ELISA, FC | Humanized IgG1, κ |
| HPAB-0848-CN | Human Anti-TNFSF14 Recombinant Antibody (clone h10D11) | ELISA, FC | Humanized IgG1, κ |
| HPAB-0849-CN | Human Anti-TNFSF14 Recombinant Antibody (clone h14G8) | ELISA, FC | Humanized IgG1, κ |
| HPAB-0850-CN | Human Anti-TNFSF14 Recombinant Antibody (clone h18B1) | ELISA, FC | Humanized IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0404-YC-S(P) | Human Anti-TNFSF14 Recombinant Antibody; scFv Fragment (HPAB-N0404-YC-S(P)) | ELISA, FC, Inhib | Human scFv |
| HPAB-0106LY-S(P) | Human Anti-TNFSF14 Recombinant Antibody; scFv Fragment (HPAB-0106LY-S(P)) | ELISA, RIA, Block, FC | Human scfv |
| HPAB-0107LY-S(P) | Human Anti-TNFSF14 Recombinant Antibody; scFv Fragment (HPAB-0107LY-S(P)) | ELISA, RIA, Block, FC | Human scfv |
| HPAB-0108LY-S(P) | Human Anti-TNFSF14 Recombinant Antibody; scFv Fragment (HPAB-0108LY-S(P)) | ELISA, RIA, Block, FC | Human scfv |
| HPAB-0109LY-S(P) | Human Anti-TNFSF14 Recombinant Antibody; scFv Fragment (HPAB-0109LY-S(P)) | ELISA, RIA, Block, FC | Human scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0404-YC-F(E) | Human Anti-TNFSF14 Recombinant Antibody; Fab Fragment (HPAB-N0404-YC-F(E)) | ELISA, FC, Inhib | Human Fab |
| HPAB-0847-CN-F(E) | Human Anti-TNFSF14 Recombinant Antibody (clone h5E10); Fab Fragment | ELISA, FC | Humanized Fab |
| HPAB-J0293-YC-F(E) | Mouse Anti-TNFSF14 Recombinant Antibody (clone m10D11); Fab Fragment | ELISA, FC, Inhib | Mouse Fab |
| HPAB-J0294-YC-F(E) | Mouse Anti-TNFSF14 Recombinant Antibody (clone m5E10); Fab Fragment | ELISA, FC, Inhib | Mouse Fab |
| HPAB-J0295-YC-F(E) | Mouse Anti-TNFSF14 Recombinant Antibody (clone m13C7); Fab Fragment | ELISA, FC, Inhib | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC1170 | CytoStream™ Rabbit Anti-TNFSF14 Recombinant Antibody (VS13-YC1170) | FC, ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC484 | Recombinant Anti-TNFSF14 Vesicular Antibody, EV Displayed (VS-0425-YC484) | Block, ELISA, FC, Cell-uptake |
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