Afuco™ Anti-TNFSF4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-223)
CAT#: AFC-TAB-223
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD252. It is a human monoclonal antibody designed for the treatment of asthma.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line BJ
Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/1331_F5_1_selected.jpg
Normal Tissue
Figure 2 IHC staining of human tonsil
Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in non-germinal center cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_4_8_selected.jpg
Normal Tissue
Figure 3 Duodenum
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_8_2.jpg
Normal Tissue
Figure 4 Colon
Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_9_3.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_6_6.jpg
Normal Tissue
Figure 6 Lymph node
Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_8_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (fHDF/TERT166, HHSteC, HUVEC TERT2, LHCN-M2)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000117586-TNFSF4
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- ELISA, FC, IP, FuncS, IF, Neut
- Conjugate
- Unconjugated
- Generic Name
- Oxelumab
- Related Disease
- Asthma
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Oxelumab"
DrugMonitor™ Anti-Oxelumab Antibody (VS-1224-YC868)Oxelumab (R 4930) is a human monoclonal antibody directed against OX40L and is currently under investigation in clinical trials for adults with mild allergic asthma. The DrugMonitor™ Anti-Oxelumab Antibody (VS-1224-YC868) is an anti-drug antibody (ADA) against Oxelumab. This drug-based antibody is raised in mice immunized with the Oxelumab. The anti-Oxelumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Oxelumab in samples.
See other products for "TNFSF4"
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0894CL | Mouse Anti-TNFSF4 Recombinant Antibody (TAB-0894CL) | ELISA | Mouse IgG |
| TAB-0895CL | Mouse Anti-TNFSF4 Recombinant Antibody (TAB-0895CL) | ELISA | Mouse IgG2b |
| TAB-0896CL | Mouse Anti-TNFSF4 Recombinant Antibody (TAB-0896CL) | ELISA | Mouse IgG |
| TAB-0270CL-F(E) | Anti-Human TNFSF4 Recombinant Antibody Fab Fragment (W66) | ELISA, WB | |
| TAB-0894CL-F(E) | Mouse Anti-TNFSF4 Recombinant Antibody; Fab Fragment (TAB-0894CL-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0897CL | Human Anti-TNFSF4 Recombinant Antibody (TAB-0897CL) | FC | Human IgG4 |
| TAB-0898CL | Human Anti-TNFSF4 Recombinant Antibody (TAB-0898CL) | FC | Human IgG |
| TAB-0899CL | Human Anti-TNFSF4 Recombinant Antibody (TAB-0899CL) | FC | Human IgG |
| TAB-0900CL | Human Anti-TNFSF4 Recombinant Antibody (TAB-0900CL) | FC | Human IgG |
| TAB-0901CL | Human Anti-TNFSF4 Recombinant Antibody (TAB-0901CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2198CQ | Rat Anti-Tnfsf4 Recombinant Antibody (NEUT-2198CQ) | Block, FC, IHC-Fr | Rat IgG2 |
| NEUT-2199CQ | Rat Anti-Tnfsf4 Recombinant Antibody (clone RM134L) | Block, FC, IP | Rat IgG2b |
| NEUT-2201CQ | Mouse Anti-Tnfsf4 Recombinant Antibody (clone OX-89) | IHC-Fr, FC, Block | Mouse IgG2a, κ |
| NEUT-2204CQ | Mouse Anti-TNFSF4 Recombinant Antibody (clone R4930) | FC, Block | Mouse IgG, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2200CQ | Rat Anti-Tnfsf4 Recombinant Antibody (clone CBL346) | Neut, WB | Rat IgG2a |
| NEUT-2202CQ | Mouse Anti-TNFSF4 Recombinant Antibody (clone CBL569) | FC, CyTOF, ICC, Neut | Mouse IgG1 |
| NEUT-2203CQ | Mouse Anti-TNFSF4 Recombinant Antibody (clone MM0505-8S23) | FC, IHC, IHC-Fr, CyTOF, Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3622 | Rabbit Anti-TNFSF4 Recombinant Antibody (clone DS3622AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0144-CN | Mouse Anti-TNFSF4 Recombinant Antibody (HPAB-0144-CN) | ELISA, FC | Mouse IgG |
| HPAB-0145-CN | Mouse Anti-TNFSF4 Recombinant Antibody (HPAB-0145-CN) | ELISA, FC | Mouse IgG |
| HPAB-0146-CN | Human Anti-TNFSF4 Recombinant Antibody (HPAB-0146-CN) | ELISA, FC | Human IgG1, κ |
| HPAB-0147-CN | Human Anti-TNFSF4 Recombinant Antibody (HPAB-0147-CN) | ELISA, FC | Human IgG1, κ |
| HPAB-0148-CN | Human Anti-TNFSF4 Recombinant Antibody (HPAB-0148-CN) | ELISA, FC | Human IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0144-CN-S(P) | Mouse Anti-TNFSF4 Recombinant Antibody; scFv Fragment (HPAB-0144-CN-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0145-CN-S(P) | Mouse Anti-TNFSF4 Recombinant Antibody; scFv Fragment (HPAB-0145-CN-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-0146-CN-S(P) | Human Anti-TNFSF4 Recombinant Antibody; scFv Fragment (HPAB-0146-CN-S(P)) | ELISA, FC | Human scFv |
| HPAB-0147-CN-S(P) | Human Anti-TNFSF4 Recombinant Antibody; scFv Fragment (HPAB-0147-CN-S(P)) | ELISA, FC | Human scFv |
| HPAB-0148-CN-S(P) | Human Anti-TNFSF4 Recombinant Antibody; scFv Fragment (HPAB-0148-CN-S(P)) | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0144-CN-F(E) | Mouse Anti-TNFSF4 Recombinant Antibody; Fab Fragment (HPAB-0144-CN-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0145-CN-F(E) | Mouse Anti-TNFSF4 Recombinant Antibody; Fab Fragment (HPAB-0145-CN-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0146-CN-F(E) | Human Anti-TNFSF4 Recombinant Antibody; Fab Fragment (HPAB-0146-CN-F(E)) | ELISA, FC | Human Fab |
| HPAB-0147-CN-F(E) | Human Anti-TNFSF4 Recombinant Antibody; Fab Fragment (HPAB-0147-CN-F(E)) | ELISA, FC | Human Fab |
| HPAB-0148-CN-F(E) | Human Anti-TNFSF4 Recombinant Antibody; Fab Fragment (HPAB-0148-CN-F(E)) | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX1137 | Mouse Anti-TNFSF4 Recombinant Antibody (clone 362CT19.3.3) | WB | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY227 | CytoStream™ Mouse Anti-TNFSF4 Recombinant Antibody (VS-0225-XY227) | FC | Mouse IgG1, kappa |
| VS13-YC1171 | CytoStream™ Rabbit Anti-TNFSF4 Recombinant Antibody (VS13-YC1171) | FC, ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7396 | Anti-TNFSF4 Immunohistochemistry Kit | IHC |
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