Afuco™ Anti-TNFSF4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-223) (CAT#: AFC-TAB-223)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD252. It is a human monoclonal antibody designed for the treatment of asthma.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/1331_F5_1_selected.jpg
(Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/1331_F5_1_selected.jpg
Figure 2 IHC staining of human tonsil
(Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in non-germinal center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_4_8_selected.jpg
(Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in non-germinal center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_4_8_selected.jpg
Figure 3 Duodenum
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_8_2.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_8_2.jpg
Figure 4 Colon
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_9_3.jpg
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_9_3.jpg
Figure 5 Testis
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_6_6.jpg
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_6_6.jpg
Figure 6 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_8_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/59579/134109_A_8_8.jpg
Figure 7 RNA cell line category: Cell line enhanced (fHDF/TERT166, HHSteC, HUVEC TERT2, LHCN-M2)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000117586-TNFSF4
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000117586-TNFSF4
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- ELISA, FC, IP, FuncS, IF, Neut
- Conjugate
- Unconjugated
- Generic Name
- Oxelumab
- Related Disease
- Asthma
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- TNFSF4; tumor necrosis factor (ligand) superfamily, member 4; tax transcriptionally activated glycoprotein 1, 34kD, TXGP1; tumor necrosis factor ligand superfamily member 4; CD252; gp34; OX 40L; OX40L
- Gene ID
- 7292
- UniProt ID
- P23510
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Oxelumab"
DrugMonitor™ Anti-Oxelumab Antibody (VS-1224-YC868)Oxelumab (R 4930) is a human monoclonal antibody directed against OX40L and is currently under investigation in clinical trials for adults with mild allergic asthma. The DrugMonitor™ Anti-Oxelumab Antibody (VS-1224-YC868) is an anti-drug antibody (ADA) against Oxelumab. This drug-based antibody is raised in mice immunized with the Oxelumab. The anti-Oxelumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Oxelumab in samples.
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Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1645z | Mouse Anti-TNFSF4 Recombinant Antibody (clone 28F11) | FC, IHC, Neut | Mouse IgG1 |
| MOB-0429ZL | Mouse Anti-TNFSF4 Recombinant Antibody (clone YC164) | Neut, FC, IHC | Mouse IgG1 |
| HPAB-0144-CN | Mouse Anti-TNFSF4 Recombinant Antibody (HPAB-0144-CN) | ELISA, FC | Mouse IgG |
| HPAB-0145-CN | Mouse Anti-TNFSF4 Recombinant Antibody (HPAB-0145-CN) | ELISA, FC | Mouse IgG |
| HPAB-0146-CN | Human Anti-TNFSF4 Recombinant Antibody (HPAB-0146-CN) | ELISA, FC | Human IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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