Mouse Anti-TP53 Recombinant Antibody (clone PAb421) (CAT#: FAMAB-1279CQ)
This product is a recombinant mouse antibody that recognizes TP53. The antibody was purified by affinity chromatography. It can be used in IHC-P, IP, WB, ELISA, IF, IHC-Fr.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
WB
Figure 1 Sympathetic Signaling Activates p53 via ATM.
Western blot of p53, MDM2, c-FOS and c-JUN in 10 µM iso-treated wt and Per1−/−; Per2m/m osteoblasts using anti-p53 PAb421, MDM2-2A10, c-FOS and c-Jun antibodies.
Lee, S., Donehower, L. A., Herron, A. J., Moore, D. D., & Fu, L. (2010). Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in mice. PloS one, 5(6), e10995.
Specifications
- Immunogen
- Synthetic peptide corresponding to aa 371-380 of human p53
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Specificity
- Mutant and wild-type p53 protein
- Species Reactivity
- Monkey, Rabbit, Human, Mouse, Rat
- Clone
- PAb421
- Applications
- WB, IF, IB
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Immonobloting, Immunofluorescence and Western Blot.
Target
- Alternative Names
- Tumor Protein P53; Phosphoprotein P53; Antigen NY-CO-13; P53; Transformation-Related Protein 53; Cellular Tumor Antigen P53; Mutant Tumor Protein 53; Li-Fraumeni Syndrome
- Gene ID
- 7157
- UniProt ID
- P04637
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-994 | Recombinant anti-TP53 antibody svFv Fragment | ELISA, Agonist | scFv |
| HPAB-0001-YC-S(P) | Mouse Anti-TP53 Recombinant Antibody (clone 70237-85); scFv Fragment | IHC, WB, ELISA | Mouse scFv |
| HPAB-0002-YC-S(P) | Mouse Anti-TP53 Recombinant Antibody (clone 240); scFv Fragment | IP, ELISA | Mouse scFv |
| HPAB-M0287-YC-S(P) | Mouse Anti-TP53 Recombinant Antibody (clone 6C4); scFv Fragment | ELISA | Mouse scFv |
| HPAB-1568WJ-S(P) | Mouse Anti-TP53 Recombinant Antibody; scFv Fragment (clone 11D3) | ELISA, WB | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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