Mouse Anti-TP53 Recombinant Antibody (clone PAb421) (CAT#: FAMAB-1279CQ)
This product is a recombinant mouse antibody that recognizes TP53. The antibody was purified by affinity chromatography. It can be used in IHC-P, IP, WB, ELISA, IF, IHC-Fr.
Specific Inquiry
WB
Figure 1 Sympathetic Signaling Activates p53 via ATM.
Western blot of p53, MDM2, c-FOS and c-JUN in 10 µM iso-treated wt and Per1−/−; Per2m/m osteoblasts using anti-p53 PAb421, MDM2-2A10, c-FOS and c-Jun antibodies.
Lee, S., Donehower, L. A., Herron, A. J., Moore, D. D., & Fu, L. (2010). Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in mice. PloS one, 5(6), e10995.
IF
Figure 2 The different p53 staining pattern in PARP-1 deficient cells.
The cells were stained with monoclonal anti-p53 PAb421 antibody.
Wesierska-Gadek, J., & Schmid, G. (2001). POLY (ADP-RIBOSE) POLYMERASE-1 REGULATES THE STABILITY OF WILD-TYPE p53 PROTEIN. Cellular and Molecular Biology Letters, 6(2), 117-140.
IB
Figure 3 PARP-1 deficient cells express AS p53 protein.
Immunoblotting was performed with anti-p53 antibody PAb421 recognizing solely RS p53.
Wesierska-Gadek, J., & Schmid, G. (2001). POLY (ADP-RIBOSE) POLYMERASE-1 REGULATES THE STABILITY OF WILD-TYPE p53 PROTEIN. Cellular and Molecular Biology Letters, 6(2), 117-140.
Specifications
- Immunogen
- Synthetic peptide corresponding to aa 371-380 of human p53
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Specificity
- Mutant and wild-type p53 protein
- Species Reactivity
- Monkey, Rabbit, Human, Mouse, Rat
- Clone
- PAb421
- Applications
- WB, IF, IB
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Immonobloting, Immunofluorescence and Western Blot.
Target
- Alternative Names
- Tumor Protein P53; Phosphoprotein P53; Antigen NY-CO-13; P53; Transformation-Related Protein 53; Cellular Tumor Antigen P53; Mutant Tumor Protein 53; Li-Fraumeni Syndrome
- Gene ID
- 7157
- UniProt ID
- P04637
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone PAb421"
See other products for "TP53"
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-994 | Recombinant anti-TP53 antibody svFv Fragment | ELISA, Agonist | scFv |
| HPAB-0001-YC-S(P) | Mouse Anti-TP53 Recombinant Antibody (clone 70237-85); scFv Fragment | IHC, WB, ELISA | Mouse scFv |
| HPAB-M0287-YC-S(P) | Mouse Anti-TP53 Recombinant Antibody (clone 6C4); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0662-YJ-S(P) | Mouse Anti-TP53 Recombinant Antibody (clone Ab421); scFv Fragment | ELISA | Mouse scFv |
| HPAB-1568WJ-S(P) | Mouse Anti-TP53 Recombinant Antibody; scFv Fragment (clone 11D3) | ELISA, WB | Mouse scFv |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PNBL-072 | Recombinant Anti-p53 VHH Single Domain Antibody (Nb139) | Inhib, IP, WB, ELISA, FuncS | Llama VHH |
| HPAB-0746-YJ-VHH | Camelid Anti-TP53 Recombinant Single Domain Antibody (CBP71YJ) | ELISA | Camelid VHH |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3644 | Rabbit Anti-TP53 Recombinant Antibody (clone DS3644AB) | IHC-P | Rabbit IgG |
| MOR-4524 | Rabbit Anti-TP53 Recombinant Antibody (clone TH32DS) | WB, IF, ICC | Rabbit IgG |
| MOR-4698 | Rabbit Anti-TP53 Recombinant Antibody (clone TH212DS) | WB, IF, ICC, FC, ChIP, FRET | Rabbit IgG |
MHC Tetramer for Cancer
Model Organism Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MD-ZBF-YC001 | Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-1.1) | WB, ICC | Mouse antibody |
| MD-ZBF-YC002 | Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-2.1) | WB, ICC, IHC | Mouse antibody |
| MD-ZBF-YC003 | Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-3.1) | WB, ICC | Mouse antibody |
| MD-ZBF-YC004 | Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-4.1) | WB, ICC | Mouse antibody |
| MD-ZBF-YC005 | Recombinant Mouse Anti-Zebrafish tp53 Antibody (ZFp53-5.1) | WB, ICC, IHC | Mouse antibody |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0001-YC-F(E) | Mouse Anti-TP53 Recombinant Antibody (clone 70237-85); Fab Fragment | IHC, WB, ELISA | Mouse Fab |
| HPAB-0002-YC-F(E) | Mouse Anti-TP53 Recombinant Antibody (clone 240); Fab Fragment | IP, ELISA | Mouse Fab |
| HPAB-0003-YC-F(E) | Mouse Anti-TP53 Recombinant Antibody (clone 246); Fab Fragment | IP, ELISA | Mouse Fab |
| HPAB-M0287-YC-F(E) | Mouse Anti-TP53 Recombinant Antibody (clone 6C4); Fab Fragment | ELISA | Mouse Fab |
| HPAB-1568WJ-F(E) | Mouse Anti-TP53 Recombinant Antibody; Fab Fragment (clone 11D3) | ELISA, WB | Mouse Fab |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0633CQ | Mouse Anti-TP53 Recombinant Antibody (clone p53-11) | WB | Mouse IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1147-CN | Mouse Anti-TP53 Recombinant Antibody (clone 6B2) | WB | Mouse IgG2b |
| MRO-1148-CN | Mouse Anti-TP53 Recombinant Antibody (clone 6B5) | WB | Mouse IgG1 |
| MRO-1149-CN | Mouse Anti-TP53 Recombinant Antibody (clone C8-A11) | WB, IF, IHC | Mouse IgG1 |
| MRO-1150-CN | Rabbit Anti-TP53 Recombinant Antibody (clone CBACN-418) | WB, IF | Rabbit IgG |
| MRO-1151-CN | Rabbit Anti-TP53 Recombinant Antibody (clone SY010-6) | WB, IF, IHC, IP | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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