AbPlus™ Anti-TRADD Magnetic Beads (VS-0724-YC467) (CAT#: VS-0724-YC467)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-TRADD specific antibody

• Target
• TRADD

• Immunogen
• Recombinant human TRADD fragment derived from E. coli.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]

• Alternative Names
• TNFRSF1A Associated Via Death Domain; TNFRSF1A-Associated Via Death Domain; Tumor Necrosis Factor Receptor Type 1 Associated Death Domain Protein; Tumor Necrosis Factor Receptor Type 1-Associated DEATH Domain Protein; Tumor Necrosis Factor Receptor-1-Associated Protein; TNFR1-Associated Death Domain Protein; TNFR1-Associated DEATH Domain Protein; Hs.89862;

• Gene ID
• 8717

• UniProt ID
• Q15628

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