AbPlus™ Anti-TRADD Magnetic Beads (VS-0724-YC467)
CAT#: VS-0724-YC467
The AbPlus Anti-TRADD Magnetic Beads (VS-0724-YC467) is an innovative affinity resin which is bound with anti-TRADD specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of TRADD protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4602/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human duodenum
Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/71341/159641_A_9_2_selected.jpg
Normal Tissue
Figure 3 Spleen
High expression in spleen
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4602/11986_B_9_4_val_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/71341/159641_B_9_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/71341/159641_A_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000102871-TRADD
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-TRADD specific antibody
- Target
- TRADD
- Immunogen
- Recombinant human TRADD fragment derived from E. coli.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]
- Alternative Names
- TNFRSF1A Associated Via Death Domain; TNFRSF1A-Associated Via Death Domain; Tumor Necrosis Factor Receptor Type 1 Associated Death Domain Protein; Tumor Necrosis Factor Receptor Type 1-Associated DEATH Domain Protein; Tumor Necrosis Factor Receptor-1-Associated Protein; TNFR1-Associated Death Domain Protein; TNFR1-Associated DEATH Domain Protein; Hs.89862;
- Gene ID
- 8717
- UniProt ID
- Q15628
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Related Diseases
Colorectal Cancer
Maturity Onset Diabetes of the Young
Related Signaling Pathways
TNF Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "TRADD"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1717z | Mouse Anti-TRADD Recombinant Antibody (clone 29C4) | FC, ICC, IHC | Mouse IgG2a |
| MOB-0229MC | Anti-Canine TRADD Antibody | WB, IF, IP, ELISA | |
| MOB-1822MZ | Recombinant Mouse Anti-Human TRADD Antibody | WB | Mouse antibody |
| VS7-0425-WR1039 | Mouse Anti-TRADD Recombinant Antibody (clone 3A1E8) | FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3667 | Rabbit Anti-TRADD Recombinant Antibody (clone DS3667AB) | WB, IHC, ICC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2343 | Anti-TRADD Immunohistochemistry Kit | IHC | |
| VS-0525-XY7487 | Anti-Human TRADD Immunohistochemistry Kit | IHC |
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