AbPlus™ Anti-TRAF4 Magnetic Beads (VS-0724-YC384) (CAT#: VS-0724-YC384)
The AbPlus Anti-TRAF4 Magnetic Beads (VS-0724-YC384) is an innovative affinity resin which is bound with anti-TRAF4 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of TRAF4 protein under native and denaturing conditions.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line RT4
(Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm, nucleoli fibrillar center & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21904/1943_G1_3_selected.jpg
(Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm, nucleoli fibrillar center & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21904/1943_G1_3_selected.jpg

Figure 2 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & nucleoli fibrillar center.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9055/963_A12_1_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & nucleoli fibrillar center.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9055/963_A12_1_selected.jpg

Figure 3 Gallbladder
(High expression in gallbladder)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52377/129872_A_4_4_val_selected.jpg
(High expression in gallbladder)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52377/129872_A_4_4_val_selected.jpg

Figure 4 Testis
(Elongated or late spermatids Staining: High Intensity: Strong Quantity:>75% Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Round or early spermatids Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52377/129872_A_6_6.jpg
(Elongated or late spermatids Staining: High Intensity: Strong Quantity:>75% Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Round or early spermatids Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52377/129872_A_6_6.jpg

Figure 5 Salivary gland
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52377/129872_B_3_1.jpg
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52377/129872_B_3_1.jpg

Figure 6 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52377/129872_A_7_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52377/129872_A_7_3.jpg

Figure 7 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52377/129872_A_9_4.jpg
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52377/129872_A_9_4.jpg

Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000076604-TRAF4
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000076604-TRAF4
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-TRAF4 specific antibody
- Target
- TRAF4
- Immunogen
- Synthetic peptide corresponding to the N-terminus of the human Traf4.
- Target Species
- Human, Mouse
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
- Alternative Names
- TNF Receptor Associated Factor 4; Cysteine-Rich Domain Associated With RING And Traf Domains Protein 1; Metastatic Lymph Node Gene 62 Protein; RING Finger Protein 83; MLN 62; CART1; MLN62;
- Gene ID
- 9618
- UniProt ID
- Q9BUZ4
Downloads
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CAT | Product Name | Application | Type |
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MOB-0835MZ | Recombinant Mouse Anti-Human TRAF4 Antibody | IHC-P | Mouse antibody |
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