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TRAPPC2
Rabbit Anti-TRAPPC2 Recombinant Antibody (clone R02-4G4)

Rabbit Anti-TRAPPC2 Recombinant Antibody (clone R02-4G4) (CAT#: VS3-FY2096)

Name: Rabbit Anti-TRAPPC2 Recombinant Antibody (clone R02-4G4)
SKU: VS3-FY2096
Rating: 5 (1 reviews)

The anti-TRAPPC2 antibody detected positive in western blot analysis of TRAPPC2 in Hela, HL-60 lysates. The recombinant monoclonal antibody demonstrates high specificity in binding to human TRAPPC2. This R02-4G4 antibody is validated for western blot analysis of TRAPPC2 in Hela, HL-60 lysates.

Tested Data
Gene Expression
Datasheet
MSDS
COA

Figure 1 Anti-TRAPPC2 Antibody (VS3-FY2096) in WB.

Figure 1 Anti-TRAPPC2 Antibody (VS3-FY2096) in WB.

The TRAPPC2 expression in Hela, HL-60 lysates were detected using the anti-TRAPPC2 by western blot assay.

Subcellular Location

Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63308/1200_G12_6_selected.jpg

Normal Tissue

Figure 2 Cerebral cortex
(Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4665/17151_B_7_5.jpg

Figure 3 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4665/17151_A_8_4.jpg

Figure 4 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4665/17151_A_7_5.jpg

Figure 5 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4665/17151_A_4_6.jpg

Figure 6 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4665/17151_A_8_8.jpg

Figure 7 Spleen
(Cells in red pulp Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Cells in white pulp Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4665/17151_B_8_4.jpg

RNA Expression

Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196459-TRAPPC2

Datasheet

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Specifications

Immunogen
Synthetic peptides of human TRAPPC2

Host Species
Rabbit

Type
Rabbit IgG

Specificity
Human TRAPPC2

Species Reactivity
Human

Clone
R02-4G4

Applications
Western Blot

MW
The calculated weight of the target protein is approximately 16 kDa, while the observed molecular weight stands at 16 kDa.

Related Disease
Spondyloepiphyseal Dysplasia Tarda, X-Linked and Spastic Paraplegia 4, Autosomal Dominant

Product Property

Purification
Affinity Purified

Format
Liquid

Concentration
Please refer to the vial label for the specific concentration.

Buffer
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% glycerol, 0.05% BSA

Preservative
0.01% Sodium azide

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

Application Notes
Western Blot: 1/500-1/1000

Target

Alternative Names
Trafficking Protein Particle Complex 2; Sedlin; SEDL; Trafficking Protein Particle Complex Subunit 2; Spondyloepiphyseal Dysplasia, Late; TRAPPC2P1

Gene ID
6399

UniProt ID
P0DI81

Sequence Similarities
Belongs to the TRAPP small subunits family. Sedlin subfamily.

Cellular Localization
Cytoplasm, Nucleus

Post Translation Modifications
Modification sites at PhosphoSitePlus (P0DI81)
Modification sites at neXtProt (NX_P0DI81)

Protein Refseq
XP_011543868.1; XP_047298307.1; XP_047298308.1; XP_054183539.1; XP_054183540.1

Function
Prevents transcriptional repression and induction of cell death by ENO1 (By similarity).
May play a role in vesicular transport from endoplasmic reticulum to Golgi.

Isotype Control

Secondary Antibody

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Rabbit Monoclonal Antibody Products

CAT	Product Name	Application	Type
MOR-3675	Rabbit Anti-TRAPPC2 Recombinant Antibody (clone DS3675AB)	WB	Rabbit IgG

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