Recombinant Anti-TSLP Biparatopic Antibody, Asymmetric hetero HC-LC (CAT#: VS-0525-YC14)

• Host Animal 1
• Human

• Host Animal 2
• Human

• Specificity
• Human TSLP

• Species Reactivity
• Human

• Type
• Asymmetric hetero HC, common LC

• Valency
• 1 + 1

• Purity
• >90%

• Purification
• Affinity purified

• Applications
• ELISA

• Concentration
• Lot specific

• Buffer
• PBS, pH 7.4

• Preservative
• No preservatives

• Storage
• Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.

• Long Name
• Thymic Stromal Lymphopoietin

• Introduction
• This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases.

• Alternative Names
• thymic stromal lymphopoietin

• Gene ID
• 85480

• UniProt ID
• Q969D9

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