Recombinant Anti-TSLP Biparatopic Antibody, Asymmetric hetero HC-LC

CAT#: VS-0525-YC14

The product is a biparatopic antibody (bpAb) specifically binding unique, non-overlapping epitopes on thymic stromal lymphopoietin (TSLP).

Gene Expression
Figure 1 IF staining of human cell line HEK 293 Figure 2 RNA cell line category: Cell line enhanced.

Specifications

  • Host Animal 1
  • Human
  • Host Animal 2
  • Human
  • Specificity
  • Human TSLP
  • Species Reactivity
  • Human
  • Type
  • Asymmetric hetero HC, common LC
  • Valency
  • 1 + 1
  • Purity
  • >90%
  • Purification
  • Affinity purified
  • Applications
  • ELISA
  • Concentration
  • Lot specific
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
  • Long Name
  • Thymic Stromal Lymphopoietin

Target

  • Introduction
  • This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases.
  • Alternative Names
  • thymic stromal lymphopoietin
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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