Rabbit Anti-TTR Recombinant Antibody (clone R05-7D9) (CAT#: VS3-FY1850)

This antibody performs western blot analysis of prealbumin in human tonsils and human placenta lysates. It is a rabbit recombinant monoclonal antibody that effectively detects human TTR. The antibody is recommended for detection of TTR protein by WB, IHC-P, IP.

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WB

Figure 1 Anti-TTR Antibody (VS3-FY1850) in WB.

Figure 1 Anti-TTR Antibody (VS3-FY1850) in WB.

The Prealbumin expression in Human tonsil, Human placenta lysates were detected using the anti-Prealbumin by western blot assay.


Specifications

  • Immunogen
  • Synthetic peptide of human prealbumin
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human TTR
  • Species Reactivity
  • Human
  • Clone
  • R05-7D9
  • Applications
  • Western Blot, Immunohistochemistry-Paraffin, Immunoprecipitation
  • MW
  • The calculated weight of the target protein is approximately 16 kDa, while the observed molecular weight stands at 16 kDa.
  • Related Disease
  • Amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome

Product Property

  • Purification
  • Affinity Purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/1000
    Immunohistochemistry: 1/50-1/100
    Immunoprecipitation: 1/20

Target

  • Alternative Names
  • Transthyretin; Prealbumin, Amyloidosis Type I; PALB; ATTR; TBPA; Epididymis Luminal Protein 111; Thyroxine-Binding Prealbumin
  • Sequence Similarities
  • Belongs to the transthyretin family.
  • Cellular Localization
  • Amyloid, Cytoplasm, Secreted
  • Post Translation Modifications
  • Not glycosylated under normal conditions. Following unfolding, caused for example by variant AMYL-TTR 'Gly-38', the cryptic Asn-118 site is exposed and glycosylated by STT3B-containing OST complex, leading to its degradation by the ER-associated degradation (ERAD) pathway.
  • Function
  • Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

Recommended Products

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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