Mouse Anti-TTR Recombinant Antibody (VS3-CJ56)

CAT#: VS3-CJ56

This product is a mouse antibody that recognizes TTR.

Gene Expression
Figure 1 IF staining of human cell line CACO-2 Figure 2 IHC staining of human hippocampus Figure 3 IHC staining of human liver Figure 4 IHC staining of human pancreas Figure 5 IHC staining of human kidney Figure 6 Liver Figure 7 Pancreas Figure 8 Kidney Figure 9 RNA cell line category: Cell line enhanced (CACO-2, EFO-21, Hep G2, U-2 OS)

Specifications

  • Immunogen
  • Recombinant fragment of human TTR (N-terminus)
  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Human TTR
  • Species Reactivity
  • Human
  • Conjugate
  • Unconjugated

Product Property

  • Purification
  • Protein G affinity purified
  • Purity
  • >95% as determined by SDS-PAGE
  • Format
  • Liquid
  • Concentration
  • 1 mg/mL (lot specific)
  • Buffer
  • 50% Glycerol, 1% BSA, PBS, pH7.4.
  • Preservative
  • 0.02% sodium azide
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • This antibody has been tested for use in ELISA (1:5000-1:20000), Western Blot (1:100-1:2000).

Target

  • Alternative Names
  • ATTR; CTS; CTS1; HEL111; HsT2651; PALB; TBPA; TTN
  • Sequence Similarities
  • Belongs to the transthyretin family.
  • Cellular Localization
  • Amyloid, Cytoplasm, Secreted
  • Post Translation Modifications
  • Not glycosylated under normal conditions. Following unfolding, caused for example by variant AMYL-TTR 'Gly-38', the cryptic Asn-118 site is exposed and glycosylated by STT3B-containing OST complex, leading to its degradation by the ER-associated degradation (ERAD) pathway.
  • Function
  • Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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Isotype Control

Secondary Antibody

Recommended Dilution Buffer

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