Human Anti-Tumor Recombinant Antibody (clone LH3) (CAT#: HPAB-1201WJ)
This product is a tumor-specific human antibody. This antibody specifically binds to an antigen present on the surface and lysosomal compartments of breast and ovarian carcinoma cells, as compared to normal fibroblasts, peripheral blood lymphocytes, melanoma cells or lung carcinoma cells. This antibody can be used to reduce neoplastic cell proliferation.
Specific Inquiry
ELISA
Figure 1 Isolation of GPC2 specific human single domain antibodies by phage display.
Monoclonal phage ELISA of the seven GPC2 binders.
ELISA
Figure 2 Monoclonal phage ELISA analysis of cross-reactivity of GPC2 binders to human GPCl and GPC3 and mouse GPC2.
FC
Figure 3 GPC2 specific CAR expression on human T cells transduced with lentiviral particles was analyzed using flow cytometry by detection of GFP fluorescence.
GPC2 specific CAR expression on human T cells transduced with lentiviral particles was analyzed using flow cytometry by detection of GFP fluorescence.
Cyt
Figure 4 CAR T cells targeting GPC2 kill neuroblastoma cells.
Cytolytic activities of GPC2 targeting CAR T cells in cell assays.
Cyt
Figure 5 The luciferase expressing SKNSH neuroblastoma cells were co-cultured with mock or GPC2 CAR-transduced T cells, and specific lysis was measured using a luminescent-based cytolytic assay.
Specifications
- Immunogen
- Monolayer of 4 × 104 paraformaldehyde-fixed H3922 cells
- Host Species
- Human
- Type
- Human IgM, κ
- Specificity
- Human Tumor
- Species Reactivity
- Human
- Clone
- LH3
- Applications
- ELISA, FC, Cyt
- Related Disease
- Tumors
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The Tumor antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Flow Cytometry, Cytotoxicity.
Target
- Alternative Names
- Tumor
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone LH3"
See other products for "Tumor"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0294-YC | Human Anti-Tumor Recombinant Antibody (clone NOV019YC) | ELISA | Human IgG |
| HPAB-J0249-YC | Human Anti-Tumor Recombinant Antibody (clone CRlG) | ELISA, IHC, FuncS | Human IgG |
| FAMAB-0020WJ | Human Anti-Tumor Recombinant Antibody (clone DP-49) | ELISA, WB | Human IgA |
| FAMAB-0021WJ | Human Anti-Tumor Recombinant Antibody (clone S12-4) | ELISA, WB | Human IgG |
| FAMAB-0022WJ | Human Anti-Tumor Recombinant Antibody (clone V3-21) | ELISA, WB | Human IgA |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0294-YC-S(P) | Human Anti-Tumor Recombinant Antibody (clone NOV019YC); scFv Fragment | ELISA | Human scFv |
| FAMAB-0020WJ-S(P) | Human Anti-Tumor Recombinant Antibody (clone DP-49); scFv Fragment | ELISA, WB | Human scFv |
| FAMAB-0021WJ-S(P) | Human Anti-Tumor Recombinant Antibody (clone S12-4); scFv Fragment | ELISA, WB | Human scFv |
| FAMAB-0022WJ-S(P) | Human Anti-Tumor Recombinant Antibody (clone V3-21); scFv Fragment | ELISA, WB | Human scFv |
| FAMAB-0023WJ-S(P) | Human Anti-Tumor Recombinant Antibody (clone V1-18); scFv Fragment | ELISA, WB | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1200WJ-F(E) | Human Anti-Tumor Recombinant Antibody (clone LH11238); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-1201WJ-F(E) | Human Anti-Tumor Recombinant Antibody (clone LH3); Fab Fragment | ELISA, FC | Human Fab |
| FAMAB-0020WJ-F(E) | Human Anti-Tumor Recombinant Antibody (clone DP-49); Fab Fragment | ELISA, WB | Human Fab |
| FAMAB-0021WJ-F(E) | Human Anti-Tumor Recombinant Antibody (clone S12-4); Fab Fragment | ELISA, WB | Human Fab |
| FAMAB-0022WJ-F(E) | Human Anti-Tumor Recombinant Antibody (clone V3-21); Fab Fragment | ELISA, WB | Human Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-1201WJ. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.