Mouse Anti-UCHL1 Recombinant Antibody (VS3-FY2912) (CAT#: VS3-FY2912)

• Host Species
• Mouse

• Type
• Mouse IgG

• Specificity
• Human and Monkey UCHL1

• Species Reactivity
• Human, Monkey

• Applications
• Western Blot, Immunocytochemistry

• Conjugate
• Unconjugated, FITC

• Related Disease
• Spastic Paraplegia 79B, Autosomal Recessive and Parkinson Disease 5, Autosomal Dominant

• Clonality
• Monoclonal Antibody

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/1000
  Immunocytochemistry: 1/50-1/200

• Alternative Names
• Ubiquitin C-Terminal Hydrolase L1; Ubiquitin Carboxyl-Terminal Esterase L1 (Ubiquitin Thiolesterase); Neuron Cytoplasmic Protein 9.5; Ubiquitin Thioesterase L1; Ubiquitin Thiolesterase; PGP 9.5; Uch-L1; PGP9.5; Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1; Epididymis Secretory Protein Li 53

• Gene ID
• 7345

• UniProt ID
• P09936

• Sequence Similarities
• Belongs to the peptidase C12 family.

• Cellular Localization
• Cytoplasm, Endoplasmic reticulum, Membrane

• Post Translation Modifications
• O-glycosylated

• Protein Refseq
• NP_004172.2

• Function
• Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.

Secondary Antibody

• 2ND-040CQ
• Goat Anti-Mouse IgG (H&L) Antibody

Isotype Control

• MRO-A1591-YJ
• Mouse IgG Isotype control, Polyclonal

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