AbPlus™ Anti-UMPS Magnetic Beads (VS-0724-YC1193) (CAT#: VS-0724-YC1193)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-UMPS specific antibody

• Target
• UMPS

• Immunogen
• Recombinant human UMPS fragment derived from E. coli.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

• Alternative Names
• Uridine Monophosphate Synthetase; UMP Synthase; Orotate Phosphoribosyl Transferase And Orotidine-5-Decarboxylase; Orotidine 5-Phosphate Decarboxylase; Orotate Phosphoribosyltransferase; Uridine 5-Monophosphate Synthase; OMPdecase; OPRTase; OPRT;

• Gene ID
• 7372

• UniProt ID
• P11172

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