Mouse Anti-UQCRC1 Recombinant Antibody (VS3-FY2913)
CAT#: VS3-FY2913
The anti-UQCRC1 antibody is a mouse recombinant monoclonal antibody that is specifically created to bind human UQCRC1 protein. It exhibits cross-reactivity with mouse, rat species. The calculated molecular weight of the protein is about 52.6 kDa. This monoclonal antibody proves valuable in disease research related to Parkinsonism With Polyneuropathy and Polyneuropathy. The antibody can be utilized for detection of UQCRC1 by Western Blot (1/500-1/2000), Immunohistochemistry (1/50-1/200) and Immunocytochemistry (1/50-1/200), Flow cytometry (1/50-1/200) and ELISA (1/1000-1/10000).
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human, Mouse and Rat UQCRC1
- Species Reactivity
- Human, Mouse, Rat
- Applications
- Western Blot, Immunohistochemistry, Immunocytochemistry, Flow cytometry, ELISA
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 52.6 kDa.
- Related Disease
- Parkinsonism With Polyneuropathy and Polyneuropathy
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/2000
Immunohistochemistry: 1/50-1/200
Immunocytochemistry: 1/50-1/200
Flow cytometry: 1/50-1/200
ELISA: 1/1000-1/10000
Target
- Alternative Names
- Ubiquinol-Cytochrome C Reductase Core Protein 1; Ubiquinol-Cytochrome-C Reductase Complex Core Protein 1; Ubiquinol-Cytochrome C Reductase Core Protein I; Complex III Subunit 1; Core Protein I; Cytochrome B-C1 Complex Subunit 1, Mitochondrial; D3S3191; UQCR1; QCR1
- Gene ID
- 7384
- UniProt ID
- P31930
- Sequence Similarities
- Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily.
- Cellular Localization
- Mitochondrion inner membrane
Peripheral membrane protein
Matrix side
- Post Translation Modifications
- Ubiquitination at Lys225 (NX_P31930 [NX_P31930-1])
Modification sites at PhosphoSitePlus (P31930)
Glycosylation from GlyGen (P31930) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_003356.2
- Function
- May be involved in the in situ processing of UQCRFS1 into the mature Rieske protein and its mitochondrial targeting sequence (MTS)/subunit 9 when incorporated into complex III (Probable).
Seems to play an important role in the maintenance of proper mitochondrial function in nigral dopaminergic neurons.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "UQCRC1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS7-0425-WR1100 | Mouse Anti-UQCRC1 Recombinant Antibody (clone 1A3D12) | WB, IHC, ICC, FC | Mouse IgG1 |
| VS7-0425-WR1101 | Mouse Anti-UQCRC1 Recombinant Antibody (clone 1B1B4) | WB, IHC, ICC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2442 | Anti-UQCRC1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7765 | Anti-Mouse UQCRC1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7764 | Anti-Human UQCRC1 Immunohistochemistry Kit | IHC |
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