Mouse Anti-UQCRC1 Recombinant Antibody (VS3-FY2913) (CAT#: VS3-FY2913)

• Host Species
• Mouse

• Type
• Mouse IgG

• Specificity
• Human, Mouse and Rat UQCRC1

• Species Reactivity
• Human, Mouse, Rat

• Applications
• Western Blot, Immunohistochemistry, Immunocytochemistry, Flow cytometry, ELISA

• Conjugate
• Unconjugated, FITC

• MW
• The molecular weight of the target protein is approximately 52.6 kDa.

• Related Disease
• Parkinsonism With Polyneuropathy and Polyneuropathy

• Clonality
• Monoclonal Antibody

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/2000
  Immunohistochemistry: 1/50-1/200
  Immunocytochemistry: 1/50-1/200
  Flow cytometry: 1/50-1/200
  ELISA: 1/1000-1/10000

• Alternative Names
• Ubiquinol-Cytochrome C Reductase Core Protein 1; Ubiquinol-Cytochrome-C Reductase Complex Core Protein 1; Ubiquinol-Cytochrome C Reductase Core Protein I; Complex III Subunit 1; Core Protein I; Cytochrome B-C1 Complex Subunit 1, Mitochondrial; D3S3191; UQCR1; QCR1

• Gene ID
• 7384

• UniProt ID
• P31930

• Sequence Similarities
• Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily.

• Cellular Localization
• Mitochondrion inner membrane
  Peripheral membrane protein
  Matrix side

• Post Translation Modifications
• Ubiquitination at Lys225 (NX_P31930 [NX_P31930-1])
  Modification sites at PhosphoSitePlus (P31930)
  Glycosylation from GlyGen (P31930) 1 site, 1 O-linked glycan (1 site)

• Protein Refseq
• NP_003356.2

• Function
• May be involved in the in situ processing of UQCRFS1 into the mature Rieske protein and its mitochondrial targeting sequence (MTS)/subunit 9 when incorporated into complex III (Probable).
  Seems to play an important role in the maintenance of proper mitochondrial function in nigral dopaminergic neurons.

Secondary Antibody

• 2ND-040CQ
• Goat Anti-Mouse IgG (H&L) Antibody

Isotype Control

• MRO-A1591-YJ
• Mouse IgG Isotype control, Polyclonal

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