Mouse Anti-VCAM1 Monoclonal Antibody (VS7-0425-WR1108) (CAT#: VS7-0425-WR1108)
This product is a mouse IgG antibody that binds to human VCAM1. The antibody can be used for WB, IHC-P, IF, and ELISA assays.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

(Immunofluorescent staining of human cell line U-2 OS shows localization to cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69867/1706_F12_18_cr57d839e75f94b_selected.jpg

(Bowman's capsule Staining: High Intensity: Strong Quantity:>75% Distal tubules Staining: Medium Intensity: Strong Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/154/2835_A_8_5.jpg

(Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/154/2835_A_6_6.jpg

(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/154/2835_A_8_8.jpg

(Cells in red pulp Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in white pulp Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/154/2835_B_7_4.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000162692-VCAM1
Specifications
- Immunogen
- Recombinant human VCAM1 fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human VCAM1
- Species Reactivity
- Human
- Molecule Class
- Cell Adhesion Molecule
- Applications
- WB, IHC-P, IF, ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis, Ascitic fluid
- Format
- Liquid
- Concentration
- 1 mg/ml
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunohistochemistry: 1:200 - 1:1000
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- CD106; INCAM-100; VCAM1; vascular cell adhesion molecule 1
- Gene ID
- 7412
- UniProt ID
- P19320
- Long Name
- Vascular Cell Adhesion Molecule 1
- Cellular Localization
- Cell membrane; Membrane; Secreted
- Post Translation Modifications
- Disulfide bond; Glycoprotein; Ubl conjugation
- Protein Refseq
- NP_001069.1
- Function
- Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation (PubMed:31310649).; Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins (PubMed:10209034).; During inflammatory responses, binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration (PubMed:22970700).; Serves also as a quality-control checkpoint for entry into bone marrow by providing a 'don't-eat-me' stamping in the context of major histocompatibility complex (MHC) class-I presentation (PubMed:35210567).
Recommended Products
Isotype Control
Secondary Antibody
Related Resources
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "VCAM1"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
NABL-061 | Recombinant Anti-Human VCAM1 VHH Single Domain Antibody | WB, ELISA, IP, FuncS | Llama VHH |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS7-0425-WR1108. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: WB, IF, IP, Neut, FuncS, ELISA, FC
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: WB, IHC, FC, Cyt, ELISA
Application: WB, IF, FuncS
Application: SPR, Inhib, FuncS
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, FuncS
Application: ELISA, Inhib, FuncS
Application: ELISA, FC, FuncS
For Research Use Only. Not For Clinical Use.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.