Afuco™ Anti-VEGFA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-465CQ)

Name: Afuco™ Anti-VEGFA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-465CQ)
SKU: AFC-TAB-465CQ
Rating: 5 (1 reviews)

CAT#: AFC-TAB-465CQ

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to VEGFA. It is a human monoclonal antibody that can be potentially used in the treatment of Cancers.

Gene Expression

Normal Tissue Figure 1 Cerebral cortex

Neuronal cells
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_B_7_5.jpg

Normal Tissue Figure 2 Thyroid gland

Glandular cells
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_B_1_5.jpg

Normal Tissue Figure 3 Colon

Glandular cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_A_7_3.jpg

Normal Tissue Figure 4 Liver

Cholangiocytes
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Hepatocytes
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_A_8_4.jpg

Normal Tissue Figure 5 Kidney

Cells in glomeruli
Staining:

Medium

Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
Cells in tubules
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_A_9_5.jpg

Normal Tissue Figure 6 Testis

Leydig cells
Staining:

High

Intensity: Strong
Quantity:>75%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_A_5_6.jpg

Normal Tissue Figure 7 Lymph node

Non-germinal center cells
Staining:

Medium

Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39240/82308_A_7_8.jpg

RNA Expression Figure 8 RNA cell line category: Cell line enhanced (hTERT-RPE1, U-87 MG)

Cell lines ordered by descending RNA expression order.

RNA Expression Figure 8 RNA cell line category: Cell line enhanced (hTERT-RPE1, U-87 MG)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000112715-VEGFA

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Specifications

Immunogen
The details of the immunogen for this antibody are not available.

Host Species
Human

Derivation
Human

Type
ADCC enhanced antibody

Specificity
Human VEGFA

Species Reactivity
Human

Applications
ELISA, IHC, FC, IP, IF, FuncS

Conjugate
Unconjugated

Generic Name
Varisacumab

Related Disease
Cancers

Product Property

Purity
>95% by SDS-PAGE

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
VPF; VEGF; MVCD1

Gene ID
7422

UniProt ID
P15692

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Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - AFC-TAB-465CQ.pdf

MSDS

MSDS - AFC-TAB-465CQ.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Protocol & Troubleshooting

Immunofluorescence (IF)

Immunohistochemistry (IHC)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

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TAB-284CQ	Human Anti-VEGFA Recombinant Antibody (TAB-284CQ)	WB	Human antibody
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TAB-284CQ-F(E)	Human Anti-VEGFA Recombinant Antibody; Fab Fragment (TAB-284CQ-F(E))	ELISA	Human Fab
TAB-465CQ	Anti-Human VEGFA Recombinant Antibody (TAB-465CQ)	ELISA, IHC, FC, IP, IF, FuncS	IgG1, κ

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TAB-306CQ	Mouse Anti-VEGFA Recombinant Antibody (TAB-306CQ)	FuncS, Inhib	Mouse IgG
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TAB-306CQ-F(E)	Mouse Anti-VEGFA Recombinant Antibody; Fab Fragment (TAB-306CQ-F(E))	ELISA, Neut	Mouse Fab

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CAT	Product Name	Application	Type
NEUT-2259CQ	Mouse Anti-VEGFA Recombinant Antibody (clone A.4.6.1)	ELISA, IP, WB, Block, FC, IHC	Mouse IgG1, κ
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CAT	Product Name	Application	Type
MOR-3835	Rabbit Anti-VEGFA Recombinant Antibody (clone DS3835AB)	FC, ICC, IF, IHC-P, IP, WB	Rabbit IgG
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MD-ZBF-YC024	Camelid Anti-VEGFA Recombinant Single Domain Antibody (MD-ZBF-YC024)	ELlSA	Camelid VHH
HPAB-0646-YJ-VHH	Camelid Anti-VEGFA Recombinant Single Domain Antibody (HPAB-0646-YJ-VHH)	ELISA, Inhib	Camelid VHH
HPAB-0647-YJ-VHH	Camelid Anti-VEGFA Recombinant Single Domain Antibody (HPAB-0647-YJ-VHH)	ELISA, Inhib	Camelid VHH
HPAB-0648-YJ-VHH	Camelid Anti-VEGFA Recombinant Single Domain Antibody (HPAB-0648-YJ-VHH)	ELISA, Inhib	Camelid VHH
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HPAB-0151-FY	Human Anti-VEGFA Recombinant Antibody (clone rhVVH)	WB, ELISA, Inhib	Human IgM

CAT	Product Name	Application	Type
HPAB-0151-FY-S(P)	Human Anti-VEGFA Recombinant Antibody (clone rhVVH); scFv Fragment	WB, ELISA, Inhib	Human scFv
HPAB-0671-CN-S(P)	Human Anti-VEGFA Recombinant Antibody; scFv Fragment (HPAB-0671-CN-S(P))	ELISA, Neut	Humanized scFv
HPAB-0169-WJ-S(P)	Human Anti-VEGFA Recombinant Antibody (clone MIL60); scFv Fragment	ELISA	Human scFv
HPAB-0512-WJ-S(P)	Human Anti-VEGFA Recombinant Antibody (clone F6); scFv Fragment	ELISA	Human scFv
HPAB-0922-WJ-S(P)	Mouse Anti-VEGFA Recombinant Antibody; scFv Fragment (HPAB-0922-WJ-S(P))	ELISA	Mouse scFv

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