Human Anti-VEGFA Recombinant Antibody (clone XPA.10.064.07) (CAT#: HPAB-J0273-YC)
The affinity matured antibodies XPA.10.064.03, XPA.10.064.04, XPA.10.064.06, XPA.10.064.07, and XPA.10.064.10 as provided herein were generated by random mutagenesis of XPA.10.064 HCDR3 and subsequent binding and functional assays. The binding affinities of the affinity matured antibodies for hVEGF165 are greater than that of Bevacizumab.
Specific Inquiry
Inhib
Figure 1 Inhibition of hVEGF165 binding to VEGF-R1 by Bevacizumab (BM1), XPA.10.064, and XPA.10.073.
WB
Figure 2 Analysis of hVEGF-|65 epitopes bound by Bevacizumab (BM1), XPA.10.064 (064), and XPA.10.072 (073).
Neut
Figure 3 Inhibition of HUVEC proliferation by XPA.10.064 lgG3.
FuncS
Figure 4 Inhibition of A673 tumor growth in vivo by XPA.10.064.07.
Specifications
- Host Species
- Human
- Type
- Human IgG2
- Specificity
- Human VEGFA
- Species Reactivity
- Human, Mouse
- Clone
- XPA.10.064.07
- Applications
- Inhib, WB, Neut, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Western Blot, Functional Assay, Inhibition and Neutralization.
Target
- Alternative Names
- Vascular Endothelial Growth Factor A; Vascular Permeability Factor; VEGF; VPF; Vascular Endothelial Growth Factor A121; Vascular Endothelial Growth Factor A165; Vascular Endothelial Growth Factor; VEGF-A; MVCD1
- Gene ID
- 7422
- UniProt ID
- P15692
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-011 | Anti-Human VEGF Recombinant Antibody (Bevacizumab) | FC, IP, ELISA, Neut, FuncS, IF, ICC | IgG1 - kappa |
| TAB-012-F(E) | Anti-Human VEGF Recombinant Antibody Fab Fragment (Ranibizumab) | IP, IF, FuncS, FC, Neut, ELISA, IHC | Fab - G1 - kappa |
| TAB-307CQ | Human Anti-VEGFA Recombinant Antibody (TAB-307CQ) | Inhib | Human IgG |
| TAB-307CQ-S(P) | Human Anti-VEGFA Recombinant Antibody; scFv Fragment (TAB-307CQ-S(P)) | ELISA, Neut | Human scFv |
| TAB-009ML | Anti-Human VEGFA Recombinant Antibody scFv Fragment (Brolucizumab) | ELISA, IHC, FC, IP, IF, Inhib | scFv, κ |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L043L | anti-VEGFA immunotoxin Ng76 (scFv)-Luffin-β | Cytotoxicity assay, Functional assay |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABW-075 | Mouse Anti-VEGFA Recombinant Antibody (clone YADS1) | ELISA | Mouse IgG |
| PABC-076 | Mouse Anti-VEGFA Recombinant Antibody (clone YADS2) | ELISA | Mouse IgG |
| HPAB-0330CQ | Mouse Anti-VEGFA Recombinant Antibody (clone mAb G6-31) | ELISA, IF, Block, FuncS | Chimeric (mouse/human) IgG |
| HPAB-0348-WJ | Human Anti-VEGFA Recombinant Antibody (clone 7F2) | ELISA | Humanized IgG |
| HPAB-0349-WJ | Human Anti-VEGFA Recombinant Antibody (clone 6B2) | ELISA | Humanized IgG |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-284CQ | Human Anti-VEGFA Recombinant Antibody (TAB-284CQ) | WB | Human antibody |
| TAB-304CQ | Anti-Human VEGFA Recombinant Antibody (2H1) | ELISA | Human antibody |
| TAB-305CQ | Anti-Human VEGFA Recombinant Antibody (2H1-32) | ELISA, WB | Human antibody |
| TAB-284CQ-F(E) | Human Anti-VEGFA Recombinant Antibody; Fab Fragment (TAB-284CQ-F(E)) | ELISA | Human Fab |
| TAB-465CQ | Anti-Human VEGFA Recombinant Antibody (Varisacumab) | ELISA, IHC, FC, IP, IF, FuncS | IgG1, κ |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-306CQ | Mouse Anti-VEGFA Recombinant Antibody (TAB-306CQ) | FuncS, Inhib | Mouse IgG |
| TAB-306CQ-S(P) | Mouse Anti-VEGFA Recombinant Antibody; scFv Fragment (TAB-306CQ-S(P)) | ELISA, Neut | Mouse scFv |
| TAB-306CQ-F(E) | Mouse Anti-VEGFA Recombinant Antibody; Fab Fragment (TAB-306CQ-F(E)) | ELISA, Neut | Mouse Fab |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0623MZ | Chicken Anti-VEGF Polyclonal IgY | WB | Chicken antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2255CQ | Mouse Anti-VEGFA Recombinant Antibody (clone CBL198) | Neut, WB | Mouse IgG1 |
| NEUT-2256CQ | Rat Anti-Vegfa Recombinant Antibody (clone 2G11-2A05) | WB, Neut, ELISA, IHC, FuncS | Rat IgG2a, κ |
| NEUT-2257CQ | Mouse Anti-VEGFA Recombinant Antibody (clone 16F1) | WB, Neut | Mouse IgG2a |
| NEUT-2258CQ | Mouse Anti-VEGFA Recombinant Antibody (clone 4B2-8) | ELISA, Neut, WB | Mouse IgG1, κ |
| NEUT-2260CQ | Mouse Anti-VEGFA Recombinant Antibody (clone CBL737) | WB, ELISA, Neut | Mouse IgG2b |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2259CQ | Mouse Anti-VEGFA Recombinant Antibody (clone A.4.6.1) | ELISA, IP, WB, Block, FC, IHC | Mouse IgG1, κ |
| NEUT-2267CQ | Mouse Anti-VEGFA Recombinant Antibody (clone A15136B) | WB, Block | Mouse IgG2b, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3835 | Rabbit Anti-VEGFA Recombinant Antibody (clone DS3835AB) | FC, ICC, IF, IHC-P, IP, WB | Rabbit IgG |
| MOR-4758 | Rabbit Anti-Vegfa Recombinant Antibody (clone TH272DS) | WB | Rabbit IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-465CQ | Afuco™ Anti-VEGFA ADCC Recombinant Antibody (Varisacumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| AFC-TAB-011 | Afuco™ Anti-VEGFA ADCC Recombinant Antibody (Bevacizumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0310-YC-VHNAR | Recombinant Shark Anti-VEGFA Single Domain Antibody (V32R) | ELISA, FC, WB | Shark vNAR |
| HPAB-N0311-YC-VHNAR | Recombinant Shark Anti-VEGFA Single Domain Antibody (V19) | ELISA, FC, WB | Shark vNAR |
| HPAB-0646-YJ-VHH | Camelid Anti-VEGFA Recombinant Single Domain Antibody (clone VEvhh1) | ELISA, Inhib | Camelid VHH |
| HPAB-0647-YJ-VHH | Camelid Anti-VEGFA Recombinant Single Domain Antibody (clone VEvhh2) | ELISA, Inhib | Camelid VHH |
| NBD-0090-YJ-VHH | Camelid Anti-VEGFA Recombinant Single Domain Antibody (Nb42) | ELISA, WB, Inhib | Camelid VHH |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0715-FY-S(P) | Mouse Anti-VEGFA Recombinant Antibody (clone AB014); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0950-FY-S(P) | Camelid Anti-VEGFA Recombinant Antibody; scFv Fragment (HPAB-0950-FY-S(P)) | Inhib | Camelid scFv |
| HPAB-0152-WJ-F(E) | Human Anti-VEGFA Recombinant Antibody; Fab Fragment (HPAB-0152-WJ-F(E)) | ELISA | Human Fab |
| HPAB-0169-WJ-F(E) | Human Anti-VEGFA Recombinant Antibody (clone MIL60); Fab Fragment | ELISA | Human Fab |
| HPAB-0922-WJ-F(E) | Mouse Anti-VEGFA Recombinant Antibody; Fab Fragment (HPAB-0922-WJ-F(E)) | ELISA | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0922-WJ-S(P) | Mouse Anti-VEGFA Recombinant Antibody; scFv Fragment (HPAB-0922-WJ-S(P)) | ELISA | Mouse scFv |
| HPAB-1956-FY-S(P) | Human Anti-VEGFA Recombinant Antibody (clone Bh21-7); scFv Fragment | IF | Humanized scFv |
| HPAB-1957-FY-S(P) | Mouse Anti-VEGFA Recombinant Antibody (clone 21-7); scFv Fragment | IF | Mouse scFv |
| HPAB-2046-FY-S(P) | Human Anti-VEGFA Recombinant Antibody (clone C1039); scFv Fragment | IA | Human scFv |
| HPAB-0677YY-S(P) | Mouse Anti-VEGFA Recombinant Antibody (clone CBV110YJ); scFv Fragment | ELISA, FuncS | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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