Recombinant Dromedary Anti-VSG Single Domain Antibody (cAbAn04) (CAT#: HPAB-1224WJ)

This product is a dromedary single domain antibody targeting Variant Surface Glycoprotein trypanosome.


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DB

Figure 1 Antigen specificity of rabbit and dromedary IgGs and dromedary VHHs.

Figure 1 Antigen specificity of rabbit and dromedary IgGs and dromedary VHHs.

Dot-blot analysis of polyclonal rabbit IgG and camel conventional antibodies (IgG1) and heavy-chain antibodies (IgG2 and IgG3) on VSGs of different classes.

Stijlemans, B., Conrath, K., Cortez-Retamozo, V., Van Xong, H., Wyns, L., Senter, P., ... & Magez, S. (2004). Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies African trypanosomes as paradigm. Journal of Biological Chemistry, 279(2), 1256-1261.

ELISA

Figure 2 Antigen specificity of rabbit and dromedary IgGs and dromedary VHHs.

Figure 2 Antigen specificity of rabbit and dromedary IgGs and dromedary VHHs.

ELISA signals on AnTat 1.1, deglycosilated AnTat 1.1, MITat 1.1, and MITat 1.5 obtained with different recombinant VHHs retrieved from pannings of the "immune VHH library.".

Stijlemans, B., Conrath, K., Cortez-Retamozo, V., Van Xong, H., Wyns, L., Senter, P., ... & Magez, S. (2004). Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies African trypanosomes as paradigm. Journal of Biological Chemistry, 279(2), 1256-1261.

ELISA

Figure 3 Carbohydrate specificity of cAb-An33.

Figure 3 Carbohydrate specificity of cAb-An33.

Trypanolysis assay in which the fate of purified trypanosomes was followed for 6 h when incubated with TNF-α (dotted line, f), or with TNF-α and cAb-An33/ml, or with TNF-α and cAbAn04.

Stijlemans, B., Conrath, K., Cortez-Retamozo, V., Van Xong, H., Wyns, L., Senter, P., ... & Magez, S. (2004). Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies African trypanosomes as paradigm. Journal of Biological Chemistry, 279(2), 1256-1261.


Specifications

  • Host Species
  • Dromedary
  • Derivation
  • Phage Display Library
  • Type
  • Dromedary VHH
  • Specificity
  • Variant Surface Glycoprotein trypanosome
  • Clone
  • cAbAn04
  • Applications
  • DB, ELISA

Applications

  • Application Notes
  • The VSG antibody has been reported in applications of Dot Blot, Enzyme-linked Immunosorbent Assay.

Target

  • Alternative Names
  • Variant surface glycoprotein; VSG

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "VSG"

Recombinant Antibody

CAT Product Name Application Type
MOB-1045 Recombinant Anti-fruit fly VSG Antibody ELISA, IF, FuncS IgG
MHH-1045 Recombinant Human Anti-fruit fly VSG Antibody FC, ELISA, FuncS IgG

Fab Fragment Antibody

scFv Fragment Antibody

CAT Product Name Application Type
MOB-1045-S(P) Recombinant Anti-fruit fly VSG Antibody scFv Fragment IP, IF, Biosensors, FuncS scFv
MHH-1045-S(P) Recombinant Human Anti-fruit fly VSG Antibody scFv Fragment ELISA, WB, IF, FuncS scFv

Single-domain Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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