Rabbit Anti-VTN Recombinant Antibody (VS3-CJ321)
CAT#: VS3-CJ321
This product is a rabbit antibody that recognizes VTN.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line CACO-2
Immunofluorescent staining of human cell line CACO-2 shows localization to endoplasmic reticulum & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60933/1261_B6_4_selected.jpg
Subcellular Location
Figure 2 IHC staining of human kidney
Immunohistochemical staining of human kidney shows distinct positivity in plasma.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60933/ihc_selected.jpg
Subcellular Location
Figure 3 IHC staining of human kidney
Immunohistochemical staining of human kidney shows distinct positivity in tubular cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16695/ihc_selected.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enriched (CACO-2)
Cell lines ordered by descending RNA expression order.
RNA Expression
Figure 4 RNA cell line category: Cell line enriched (CACO-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000109072-VTN
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Specifications
- Immunogen
- Recombinant protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat VTN
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, ICC, IF, IHC
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- 40% Glycerol, 1% BSA, TBS, pH7.4.
- Preservative
- 0.05% sodium azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- This antibody has been tested for use in Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry.
Target
- Alternative Names
- VN; VNT; V75
- Gene ID
- 7448
- UniProt ID
- P04004
- Cellular Localization
- Secreted
- Post Translation Modifications
- Sulfated on tyrosine residues.
N- and O-glycosylated.
Phosphorylation on Thr-69 and Thr-76 favors cell adhesion and spreading.
It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both.
Phosphorylation sites are present in the extracellular medium.
- Protein Refseq
- NP_000629.3
- Function
- Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.
Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "VTN"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1159z | Mouse Anti-VTN Recombinant Antibody (clone 10B4) | WB, ELISA, FuncS | Mouse IgG1 |
| VS3-WK114 | Mouse Anti-VTN Recombinant Antibody (clone G11-E8) | WB, IHC, FC | Mouse IgG2b |
| VS3-XY1591 | Mouse Anti-VTN Recombinant Antibody (clone 1G11E8) | ELISA, WB, IHC, FC | Mouse IgG2b |
| VS3-XY1592 | Mouse Anti-VTN Recombinant Antibody (clone 2G112B3) | ELISA, WB, IHC, FC | Mouse IgG2b |
| VS-0923-FY155 | Recombinant Mouse Anti-VTN Antibody (VS-0923-FY155) | ELISA, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-2276CQ | Mouse Anti-VTN Recombinant Antibody (clone 615-1D1-44) | Block, ELISA, WB | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3859 | Rabbit Anti-VTN Recombinant Antibody (clone DS3859AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX1240 | Mouse Anti-VTN Recombinant Antibody (clone 389CT23.2.1.3) | WB | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2479 | Anti-VTN Immunohistochemistry Kit | IHC | |
| VS-0525-XY7882 | Anti-Mouse VTN Immunohistochemistry Kit | IHC | |
| VS-0525-XY7883 | Anti-Bovine VTN Immunohistochemistry Kit | IHC | |
| VS-0525-XY7884 | Anti-Rat VTN Immunohistochemistry Kit | IHC |
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