Mouse Anti-VZV gH Recombinant Antibody (clone RM-2D6) (CAT#: FAMAB-0726WJ)

This product is a mouse monoclonal antibody targeting Varicella-zoster virus. This antibody can be used in a variety of applications, such as ELISA, WB, Neut.


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Figure 1 VZV gH-specific monoclonal antibodies.

Figure 1 VZV gH-specific monoclonal antibodies.

Sullivan, N. L., Reuter-Monslow, M. A., Sei, J., Durr, E., Davis, C. W., Chang, C., ... & Vora, K. A. (2018). Breadth and functionality of varicella-zoster virus glycoprotein-specific antibodies identified after Zostavax vaccination in humans. Journal of Virology, 92(14), e00269-18.

Figure 2 Representative well images for samples treated with complement.

Figure 2 Representative well images for samples treated with complement.

PGS buffer was used as a negative control.

Sullivan, N. L., Reuter-Monslow, M. A., Sei, J., Durr, E., Davis, C. W., Chang, C., ... & Vora, K. A. (2018). Breadth and functionality of varicella-zoster virus glycoprotein-specific antibodies identified after Zostavax vaccination in humans. Journal of Virology, 92(14), e00269-18.

Figure 3 Cumulative data for non-gE antibodies.

Figure 3 Cumulative data for non-gE antibodies.

Black bars represent antibodies added at 10 μg/ml, and green bars represent the same antibodies added at 1 μg/ml.

Sullivan, N. L., Reuter-Monslow, M. A., Sei, J., Durr, E., Davis, C. W., Chang, C., ... & Vora, K. A. (2018). Breadth and functionality of varicella-zoster virus glycoprotein-specific antibodies identified after Zostavax vaccination in humans. Journal of Virology, 92(14), e00269-18.

Figure 4 Cell spread inhibition curves with IC50 values (μg/ml) with anti-gH or irrelevant MAbs, with (left) or without (right) complement added.

Figure 4 Cell spread inhibition curves with IC50 values (μg/ml) with anti-gH or irrelevant MAbs, with (left) or without (right) complement added.

Sullivan, N. L., Reuter-Monslow, M. A., Sei, J., Durr, E., Davis, C. W., Chang, C., ... & Vora, K. A. (2018). Breadth and functionality of varicella-zoster virus glycoprotein-specific antibodies identified after Zostavax vaccination in humans. Journal of Virology, 92(14), e00269-18.


Specifications

  • Immunogen
  • VZV antigens
  • Host Species
  • Mouse
  • Derivation
  • Hybridoma
  • Type
  • Mouse IgG1, κ
  • Specificity
  • VZV gH
  • Species Reactivity
  • Varicella-zoster virus
  • Clone
  • RM-2D6
  • Applications
  • ELISA, WB, Neut
  • Related Disease
  • Herpes zoster

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Varicella-zoster virus; VZV; Varicella-zoster virus glycoprotein H; VZV gH

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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