AbPlus™ Anti-WDR5 Magnetic Beads (D547)

CAT#: VS-0424-XY275

The AbPlus Anti-WDR5 Magnetic Beads (D547) is an innovative affinity resin which is bound with anti-WDR5 specific antibody (D547). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of WDR5 protein under native and denaturing conditions.

Gene Expression
Figure 1 IF staining of human cell line U-2 OS Figure 2 IF staining of human cell line HeLa Figure 3 IF staining of human cell line PC-3 Figure 4 RNA cell line category: Low cell line specificity Figure 4 RNA cell line category: Low cell line specificity

Specifications

  • Applications
  • Immunoprecipitation-Mass Spectrometry
  • Matrix
  • Magrose bead (> 50 μmol/mL gel)
  • Bead Ligand
  • Anti-WDR5 specific antibody (D547)
  • Target
  • WDR5
  • Target Species
  • Human
  • Antibody Clone
  • D547
  • Bead Capacity
  • 20-30 mg/mL binding antibody
  • Bead size
  • 10-37 μm
  • Stability
  • pH 2-14
  • Format
  • 20% Suspension
  • Buffer
  • PBS, pH 7.4, with 1% BSA
  • Preservative
  • 0.03% Proclin 300
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.
  • Alternative Names
  • WDR5; SWD3; BIG-3; CFAP89; WD repeat domain 5; WD repeat-containing protein 5; BMP2-induced 3-kb gene protein; SWD3, Set1c WD40 repeat protein, homolog; WD-repeat protein 5; cilia and flagella associated protein 89
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