AbPlus™ Anti-WDR5 Magnetic Beads (D547) (CAT#: VS-0424-XY275)

• Applications
• Immunoprecipitation-Mass Spectrometry

• Matrix
• Magrose bead (> 50 μmol/mL gel)

• Bead Ligand
• Anti-WDR5 specific antibody (D547)

• Target
• WDR5

• Target Species
• Human

• Antibody Clone
• D547

• Bead Capacity
• 20-30 mg/mL binding antibody

• Bead size
• 10-37 μm

• Stability
• pH 2-14

• Format
• 20% Suspension

• Buffer
• PBS, pH 7.4, with 1% BSA

• Preservative
• 0.03% Proclin 300

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.

• Alternative Names
• WDR5; SWD3; BIG-3; CFAP89; WD repeat domain 5; WD repeat-containing protein 5; BMP2-induced 3-kb gene protein; SWD3, Set1c WD40 repeat protein, homolog; WD-repeat protein 5; cilia and flagella associated protein 89

• Gene ID
• 11091

• UniProt ID
• P61964

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