Mouse Anti-WT1 Recombinant Antibody (VS3-CJ752) (CAT#: VS3-CJ752)
This product is a mouse antibody that recognizes human WT1.
Specific Inquiry
Specifications
- Immunogen
- KLH-conjugated synthetic peptide encompassing a sequence within human Wilms Tumor 1
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human WT1
- Species Reactivity
- Human
- Applications
- WB, IHC
- Conjugate
- Unconjugated
Product Property
- Purification
- Immunogen affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 0.2% BSA, PBS.
- Preservative
- 0.01% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipped at 4°C
Applications
- Application Notes
- This antibody has been tested for use in Western Blot (1:500-1:1000), Immunohistochemistry (1:100-1:300).
Target
- Alternative Names
- GUD; AWT1; WAGR; WT-1; WT33; NPHS4; WIT-2
- Gene ID
- 7490
- UniProt ID
- P19544
- Sequence Similarities
- Belongs to the EGR C2H2-type zinc-finger protein family.
- Cellular Localization
- Cytoplasm, Nucleus
- Protein Refseq
- NP_000369.3; NP_001185480.1; NP_001185481.1
- Function
- Transcription factor that plays an important role in cellular development and cell survival (PubMed:7862533).
Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3' (PubMed:7862533, PubMed:17716689, PubMed:25258363).
Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors (PubMed:15520190).
Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing (PubMed:16934801).
Isoform 1 has lower affinity for DNA, and can bind RNA (PubMed:19123921).
Recommended Products
Isotype Control
Secondary Antibody
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "WT1"
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G065R | Anti-WT1 immunotoxin 6F-H2 (IgG)-RTA | Cytotoxicity assay, Function study |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0344MZ | Recombinant Mouse Anti-Human Wilms Tumor 1 Antibody (clone 7G-H3) | IHC | Mouse antibody |
| MOB-117CQ | Human Anti-WT1 Recombinant Antibody (MOB-117CQ) | ELISA, WB, FC, FuncS | Human IgG1 |
| MRO-1597-CN | Rabbit Anti-WT1 Recombinant Antibody (clone CBACN-584) | WB, IF, IHC, FC | Rabbit IgG |
| ZG-0176C | Mouse Anti-WT1 Recombinant Antibody (clone ABT-WT1) | IHC-P, IF | Mouse IgG |
| ZG-0177C | Mouse Anti-WT1 Recombinant Antibody (clone PT0264) | IHC-P, IF | Mouse IgG |
MHC Tetramer for Cancer
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3886 | Rabbit Anti-WT1 Recombinant Antibody (clone DS3886AB) | WB, IP | Rabbit IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS3-CJ752. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.