Mouse Anti-XRCC1 Recombinant Antibody (clone 7B4C12) (CAT#: VS7-0425-WR1136)
This product is a mouse IgG1 antibody that binds to human XRCC1. The antibody 7B4C12 recognizes specific amino acid domain of human XRCC1 (AA:1-150). It can be used for WB, IHC, and FC assays.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Immunogen
- Recombinant human XRCC1 (AA:1-150) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human XRCC1
- Species Reactivity
- Human
- Clone
- 7B4C12
- Molecule Class
- Dna Repair Protein
- Applications
- WB, IHC, FC
- Conjugate
- Unconjugated
- Related Disease
- Spinocerebellar ataxia, autosomal recessive, 26 (SCAR26)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunohistochemistry-Paraffin: 1:200 - 1:1000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- XRCC1; DNA Repair Protein XRCC1; RCC; X-Ray Repair Complementing Defective Repair In Chinese Hamster Cells 1; X-Ray Repair Cross-Complementing Protein 1
- Gene ID
- 7515
- UniProt ID
- P18887
- Long Name
- X-ray repair cross complementing 1
- Cellular Localization
- Chromosome; Nucleus
- Post Translation Modifications
- Isopeptide bond; Phosphoprotein; Ubl conjugation
- Protein Refseq
- NP_006288.2
- Function
- Scaffold protein involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes (PubMed:11163244, PubMed:28002403).; Negatively regulates ADP-ribosyltransferase activity of PARP1 during base-excision repair in order to prevent excessive PARP1 activity (PubMed:28002403, PubMed:34102106, PubMed:34811483).; Recognizes and binds poly-ADP-ribose chains: specifically binds auto-poly-ADP-ribosylated PARP1, limiting its activity (PubMed:14500814, PubMed:34102106, PubMed:34811483).
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3628z | Mouse Anti-XRCC1 Recombinant Antibody (clone 41H8) | WB, IP, IF, IHC, ELISA | Mouse IgG2b |
| MOB-2157CT | Recombinant Mouse anti-Human XRCC1 Monoclonal antibody (44-3-6) | FC, ICC/IF, IHC-Fr, IHC-P, IP, WB | |
| ZG-0513F | Mouse Anti-XRCC1 Recombinant Antibody (ZG-0513F) | WB | Mouse IgG |
| VS3-QX1251 | Mouse Anti-XRCC1 Recombinant Antibody (clone 3F6-G7-F7) | WB | Mouse IgG1 |
| VS3-FY2103 | Rabbit Anti-XRCC1 Recombinant Antibody (clone R02-0B0) | WB, IF | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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