Mouse Anti-XRCC1 Recombinant Antibody (clone 7B4C12)
CAT#: VS7-0425-WR1136
This product is a mouse IgG1 antibody that binds to human XRCC1. The antibody 7B4C12 recognizes specific amino acid domain of human XRCC1 (AA:1-150). It can be used for WB, IHC, and FC assays.
Specifications
- Immunogen
- Recombinant human XRCC1 (AA:1-150) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human XRCC1
- Species Reactivity
- Human
- Clone
- 7B4C12
- Molecule Class
- Dna Repair Protein
- Applications
- WB, IHC, FC
- Conjugate
- Unconjugated
- Related Disease
- Spinocerebellar ataxia, autosomal recessive, 26 (SCAR26)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunohistochemistry-Paraffin: 1:200 - 1:1000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- XRCC1; DNA Repair Protein XRCC1; RCC; X-Ray Repair Complementing Defective Repair In Chinese Hamster Cells 1; X-Ray Repair Cross-Complementing Protein 1
- Gene ID
- 7515
- UniProt ID
- P18887
- Long Name
- X-ray repair cross complementing 1
- Cellular Localization
- Chromosome; Nucleus
- Post Translation Modifications
- Isopeptide bond; Phosphoprotein; Ubl conjugation
- Protein Refseq
- NP_006288.2
- Function
- Scaffold protein involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes (PubMed:11163244, PubMed:28002403).; Negatively regulates ADP-ribosyltransferase activity of PARP1 during base-excision repair in order to prevent excessive PARP1 activity (PubMed:28002403, PubMed:34102106, PubMed:34811483).; Recognizes and binds poly-ADP-ribose chains: specifically binds auto-poly-ADP-ribosylated PARP1, limiting its activity (PubMed:14500814, PubMed:34102106, PubMed:34811483).
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Reconstitution Buffer
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
See other products for "XRCC1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2157CT | Recombinant Mouse anti-Human XRCC1 Monoclonal antibody (44-3-6) | FC, ICC, IF, IHC-Fr, IHC-P, IP, WB | |
| MRO-1606-CN | Rabbit Anti-XRCC1 Recombinant Antibody (clone JA11-47) | WB, IHC | Rabbit IgG |
| ZG-0513F | Mouse Anti-XRCC1 Recombinant Antibody (ZG-0513F) | WB | Mouse IgG |
| VS3-FY2103 | Rabbit Anti-XRCC1 Recombinant Antibody (clone R02-0B0) | WB, IF | Rabbit IgG |
| VS7-0425-WR1137 | Mouse Anti-XRCC1 Recombinant Antibody (clone 4D10D3) | WB, IHC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3893 | Rabbit Anti-XRCC1 Recombinant Antibody (clone DS3893AB) | WB, IHC, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC167 | AbPlus™ Anti-XRCC1 Magnetic Beads (VS-0724-YC167) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7965 | Anti-XRCC1 Immunohistochemistry Kit | IHC |
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