Rabbit Anti-XRCC1 Recombinant Antibody (clone R05-7K6)
CAT#: VS3-XY3542
It is a recombinant rabbit antibody specific for XRCC1 (X-ray repair cross complementing 1), which negatively regulates ADP-ribosyltransferase activity of PARP1 during base-excision repair. The antibody specifically targets human, mouse and rat XRCC1. This product has been tested using Western Blot, Immunohistochemistry-Paraffin, Immunocytochemistry or Immunofluorescence.
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat XRCC1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R05-7K6
- Applications
- WB, IHC-P, ICC, IF
- Related Disease
- Spinocerebellar Ataxia
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IF: 1/50-1/200
Target
- Alternative Names
- RCC; SCAR26
- Gene ID
- 7515
- UniProt ID
- P18887
- Long Name
- X-ray repair cross complementing 1
- Cellular Localization
- Nucleus, Chromosome
- Post Translation Modifications
- Sumoylated. (P18887-XRCC1_HUMAN)
Glycosylation at Thr296, Thr440, Ser446, Ser447, and Thr453 (NX_P18887 [NX_P18887-1])
Modification sites at PhosphoSitePlus (P18887)
Glycosylation from GlyGen (P18887) 6 sites, 2 O-linked glycans (6 sites)
- Protein Refseq
- NP_006288.2
- Function
- Scaffold protein involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes (PubMed:11163244, 28002403).
Negatively regulates ADP-ribosyltransferase activity of PARP1 during base-excision repair in order to prevent excessive PARP1 activity (PubMed:34102106, 34811483, 28002403).
Recognizes and binds poly-ADP-ribose chains: specifically binds auto-poly-ADP-ribosylated PARP1, limiting its activity.
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS3-XY3542. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "XRCC1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2157CT | Recombinant Mouse anti-Human XRCC1 Monoclonal antibody (44-3-6) | FC, ICC, IF, IHC-Fr, IHC-P, IP, WB | |
| VS3-QX1251 | Mouse Anti-XRCC1 Recombinant Antibody (clone 3F6-G7-F7) | WB | Mouse IgG1 |
| VS3-FY2103 | Rabbit Anti-XRCC1 Recombinant Antibody (clone R02-0B0) | WB, IF | Rabbit IgG |
| VS7-0425-WR1136 | Mouse Anti-XRCC1 Recombinant Antibody (clone 7B4C12) | WB, IHC, FC | Mouse IgG1 |
| VS7-0425-WR1137 | Mouse Anti-XRCC1 Recombinant Antibody (clone 4D10D3) | WB, IHC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3893 | Rabbit Anti-XRCC1 Recombinant Antibody (clone DS3893AB) | WB, IHC, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC167 | AbPlus™ Anti-XRCC1 Magnetic Beads (VS-0724-YC167) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7965 | Anti-XRCC1 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: FC, IHC, FuncS, Inhib, Cyt
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
-2-1.png)
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: ELISA, Neut, FuncS
Application: ELISA, IP, WB, IHC, IF, FuncS
Application: FuncS, Inhib, IP, ELISA
Application: ELISA, FC, IHC, Neut
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
