Rabbit Anti-YES1 Recombinant Antibody (VS13-YC1234) (CAT#: VS13-YC1234)

• Immunogen
• Recombinant human Yes1.

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human, Mouse and Rat YES1

• Species Reactivity
• Human, Mouse, Rat

• Applications
• WB, IHC-P, ICC, IF, IP

• Conjugate
• NONE

• Related Disease
• Sarcoma and Colorectal Cancer

• Clonality
• Monoclonal

• Purification
• Affinity Chromatography purified

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Buffer
• PBS (pH 7.4) containing 150 mM NaCl and 50% Glycerol.

• Preservative
• 0.02% Sodium azide

• Storage
• Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Shipping with ice pack.

• Application Notes
• Western blot (WB): 1/500-1/1000
  Immunohistochemistry (IHC): 1/50-1/100
  Immunofluorescence (IF): 1/50-1/200
  Immunoprecipitation (IP): 1/50

• Alternative Names
• YES Proto-Oncogene 1, Src Family Tyrosine Kinase; V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1; Proto-Oncogene C-Yes; EC 2.7.10.2; P61-YES; Yes; YES1 Proto-Oncogene, Src Family Tyrosine Kinase; Proto-Oncogene Tyrosine-Protein Kinase YES;

• Gene ID
• 7525

• UniProt ID
• P07947

• Long Name
• YES Proto-Oncogene 1, Src Family Tyrosine Kinase

• Sequence Similarities
• Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.

• Cellular Localization
• Cell membrane; Cytoplasm; Cytoskeleton; Membrane

• Protein Refseq
• XP_005258196.1; XP_016881449.1; XP_024307011.1; XP_024307012.1; XP_024307013.1

• Function
• Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. Stimulation by receptor tyrosine kinases (RTKs) including EGFR, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates.

Secondary Antibody

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-061CQ
• Sheep Anti-Rabbit IgG (H&L) Antibody

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

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