AbPlus™ Anti-YWHAE Magnetic Beads (VS-0724-YC1346) (CAT#: VS-0724-YC1346)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-YWHAE specific antibody

• Target
• YWHAE

• Immunogen
• Recombinant human 14-3-3 epsilon/YWHAE, aa 1-255.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]

• Alternative Names
• Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon; Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein, Epsilon Polypeptide; 14-3-3 Epsilon; 14-3-3E; Tyrosine 3/Tryptophan 5 -Monooxygenase Activation Protein, Epsilon Polypeptide; Mitochondrial Import Stimulation Factor L Subunit; Protein Kinase C Inhibitor Protein-1;

• Gene ID
• 7531

• UniProt ID
• P62258

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