What are the primary research applications of the Mouse Anti-Z-DNA Recombinant Antibody?

This antibody is primarily used for detecting Z-DNA structures in ELISA assays. It provides researchers with a powerful tool to study DNA conformational changes and their role in gene expression regulation under various conditions.

Why is Z-DNA an important target for research?

Z-DNA is a left-handed DNA conformation that pops up transiently in cells. Its presence is associated with gene regulation and genomic hotspots for transcription. Understanding these mechanisms is crucial for elucidating gene expression patterns and potential mutagenesis processes.

Mouse Anti-Z-DNA Recombinant Antibody (clone Z22)

Product Property

Purity
>95% as determined by SDS-PAGE and HPLC analysis

Concentration
Please refer to the vial label for the specific concentration.

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

See other products for "Z-DNA"

CAT	Product Name	Application	Type
FAMAB-0366CQ	Mouse Anti-Z-DNA Recombinant Antibody (clone Z44)	ELISA	Mouse IgG2a

CAT

Product Name

Application

Type

FAMAB-0366CQ

Mouse Anti-Z-DNA Recombinant Antibody (clone Z44)

ELISA

Mouse IgG2a

Customer Reviews and Q&As

CAT	Product Name	Application	Type
FAMAB-0365CQ-F(E)	Mouse Anti-Z-DNA Recombinant Antibody (clone Z22); Fab Fragment	ELISA	Mouse Fab
FAMAB-0366CQ-F(E)	Mouse Anti-Z-DNA Recombinant Antibody (clone Z44); Fab Fragment	ELISA	Mouse Fab

CAT	Product Name	Application	Type
FAMAB-0365CQ-S(P)	Mouse Anti-Z-DNA Recombinant Antibody (clone Z22); scFv Fragment	ELISA	Mouse scFv
FAMAB-0366CQ-S(P)	Mouse Anti-Z-DNA Recombinant Antibody (clone Z44); scFv Fragment	ELISA	Mouse scFv

Customer Review Q&As

Reliable Results Every Time

We have been using this antibody for ELISA assays focusing on gene regulation via DNA structural changes. Its consistency and specificity have been impressive, supporting our studies on how Z-DNA influences gene expression and potentially highlighting regions of genomic instability.

Accuracy in Z-DNA Detection

As an integral part of our genomic studies, this antibody's precision in locating Z-DNA forms has shed light on its regulatory functions. This tool is crucial for discovering how DNA's shape affects biological outcomes and cellular adaptations.

Cite This Product

To accurately reference this product in your publication, please use the following citation information:

(Creative Biolabs Cat# FAMAB-0365CQ, RRID: AB_3111328)