APC-H-2 IAb/Mouse Myelin oligodendrocyte glycoprotein (GWYRSPFSRVVH) MHC Tetramer

CAT#: MHC-YF1570

This product is a MHC tetramer of biotinylated peptide/MHC complex composed Myelin oligodendrocyte glycoprotein-derived peptide of GWYRSPFSRVVH sequence covering 38-49 and H-2 IAb molecule. The pMHC tetramer recognizes CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.

Specifications

  • Allele
  • H-2 IAb
  • Class
  • Class II
  • MHC Species
  • Mouse
  • Antigen
  • Myelin oligodendrocyte glycoprotein
  • Antigen Species
  • Mouse
  • Peptide
  • GWYRSPFSRVVH
  • Range
  • 38-49
  • Conjugate
  • APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.
  • Alternative Names
  • MOG; myelin oligodendrocyte glycoprotein; BTN6; BTNL11; MOGIG2; NRCLP7
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