APC-B*08:01/HIV Env (YLKDQQLL) MHC Tetramer (CAT#: MHC-CN0630)
Specific Inquiry
Specifications
- Allele
- B*08:01
- Class
- Class I
- Antigen
- Env
- Antigen Species
- HIV
- Peptide
- YLKDQQLL
- Conjugate
- APC
- Application
- FCM, IHC
Target
- Antigen Introduction
- The env gene codes for the gp160 protein which forms a homotrimer, and is cleaved into gp120 and gp41 by the host cell protease, Furin. To form an active fusion protein, gp120 and gp41 polypeptides remain non-covalently bound together, but this interaction is often not stable, leading to shed, soluble gp120 and membrane-bound, gp41 'stumps'. Separately, cleavage by furin is inefficient, and virions often are released with inactive, uncleaved gp160. Because of the high prevalence of these inactive forms, the immune system often produces antibodies which target inactive Env, rather than active forms of the envelope protein.
- Alternative Names
- ENV; gp160; envelope glycoprotein; Envelope surface glycoprotein gp160; precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain
- Gene ID
- 155971
- UniProt ID
- P04578
Downloads
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Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L012R | anti-env immunotoxin 907 (IgG)-RTA | Cytotoxicity assay, Functional assay |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-193 | Recombinant Human Anti-HIV-1 gp41-M-MAT Antibody | Neut, FuncS | IgG |
| PABZ-141 | Human Anti-ENV Recombinant Antibody (clone 2F5) | Neut | Human IgG |
| PABZ-160 | Recombinant Human Anti-HIV-1 gp120 Antibody (PGT123) | FACS, Neut | IgG |
| PABZ-161 | Recombinant Human Anti-HIV-1 gp120 Antibody (PGT122) | FACS, Neut | IgG |
| PABZ-168 | Recombinant Human Anti-HIV-1 gp120 Antibody (PGT 135) | ELISA, Neut | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-193 | Recombinant Human Anti-HIV-1 gp41-M-MAT Antibody scFv Fragment | Neut, FuncS | scFv |
| PSBL-435 | Recombinant Human Anti-DENV Env Antibody scFv Fragment (EDE1 A11) | Neut | scFv |
| PSBL-436 | Human Anti-Env Recombinant Antibody; scFv Fragment (PSBL-436) | Neut | Human scFv |
| PSBL-437 | Human Anti-Env Recombinant Antibody; scFv Fragment (PSBL-437) | Neut | Human scFv |
| PSBL-438 | Human Anti-Env Recombinant Antibody; scFv Fragment (PSBL-438) | Neut | Human scFv |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PNBL-020 | Recombinant Anti-HIV ENV VHH Single Domain Antibody (JM4) | ELISA, SPR, Neut, FuncS | Llama VHH |
| PNBL-021 | Recombinant Anti-HIV-1 ENV VHH Single Domain Antibody (2H10) | Neut, WB, ELISA, FuncS | Llama VHH |
| PNBL-059 | Recombinant Anti-HIV-1 gp120 VHH Single Domain Antibody (D7) | ELISA, Inhib | Llama VHH |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-435 | Recombinant Human Anti-DENV Env Antibody Fab Fragment (EDE1 A11) | Neut | Fab |
| PFBL-436 | Human Anti-Env Recombinant Antibody; Fab Fragment (PFBL-436) | Neut | Human Fab |
| PSBZ-168 | Recombinant Human Anti-HIV-1 gp120 Antibody scFv Fragment (PGT 135) | ELISA, Neut | scFv |
| PSBZ-169 | Recombinant Human Anti-HIV-1 gp120 Antibody scFv Fragment (45-46M2) | ELISA, Neut | scFv |
| PSBZ-205 | Recombinant Human Anti-HIV-1 gp120 Antibody scFv Fragment (PGT121) | Neut, ELISA | scFv |
MHC Tetramer for Virology
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF410 | A*02:01/HIV Env (SLLNATAIAV) MHC Pentamer | FCM | |
| MHC-YF411 | A*29:02/HIV Env (SFDPIPIHY) MHC Pentamer | FCM | |
| MHC-YF412 | A*29:02/HIV Env (SFNCRGEFFY) MHC Pentamer | FCM | |
| MHC-YF413 | B*08:01/HIV Env (YLKDQQLL) MHC Pentamer | FCM | |
| MHC-YF497 | H-2Dd/HIV IIIB gp120 (RGPGRAFVTI) MHC Pentamer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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