B*08:01/HIV Env (YLKDQQLL) MHC Pentamer (CAT#: MHC-YF413)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed Env-derived peptide of YLKDQQLL sequence covering 586-593 and B*08:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
Specifications
- Allele
- B*08:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- Env
- Antigen Species
- HIV
- Peptide
- YLKDQQLL
- Range
- 586-593
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- Envelope glycoprotein gp160: Oligomerizes in the host endoplasmic reticulum into predominantly trimers. In a second time, gp160 transits in the host Golgi, where glycosylation is completed. The precursor is then proteolytically cleaved in the trans-Golgi and thereby activated by cellular furin or furin-like proteases to produce gp120 and gp41.
- Alternative Names
- Env polyprotein; env; Envelope glycoprotein gp160
- Gene ID
- 155971
- UniProt ID
- A0A343R245
Downloads
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