BV421-DRB1*03:01/Human GroEL (MAKTIAYDEEARR) MHC Tetramer

CAT#: MHC-YF1483

This product is a MHC tetramer of biotinylated peptide/MHC complex composed GroEL-derived peptide of MAKTIAYDEEARR sequence covering 1-13 and DRB1*03:01 molecule. The pMHC tetramer recognizes CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.

Specifications

  • Allele
  • DRB1*03:01
  • Class
  • Class II
  • MHC Species
  • Human
  • Antigen
  • GroEL
  • Antigen Species
  • Mycobacterium tuberculosis
  • Peptide
  • MAKTIAYDEEARR
  • Range
  • 1-13
  • Conjugate
  • BV421
  • Application
  • FCM

Target

  • Antigen Introduction
  • Prevents aggregation of substrate proteins and promotes their refolding. Functions in the absence of co-chaperone CH10 and ATP. May mediate association of bacteria with macrophages; recombinant protein competitively inhibits the association of M.tuberculosis with mouse bone marrow-derived macrophages.
  • Alternative Names
  • 60 kDa chaperonin 1; GroEL protein 1; Protein Cpn60-1, groEL
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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