DRB1*03:01/Human E2 (MEAIAKRLDACQDQLLELYE) MHC Tetramer (CAT#: MHC-YF876)
This product is a MHC tetramer of biotinylated peptide/MHC complex composed E2-derived peptide of MEAIAKRLDACQDQLLELYE sequence covering 1-20 and DRB1*03:01 molecule. The pMHC tetramer recognizes CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Specific Inquiry
Specifications
- Allele
- DRB1*03:01
- Class
- Class II
- Antigen
- E2
- Antigen Species
- HPV
- Peptide
- MEAIAKRLDACQDQLLELYE
- Range
- 1-20
- Application
- FCM
Target
- Antigen Introduction
- Plays a role in the initiation of viral DNA replication. A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity. Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA. E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome. Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box. Repression occurs by sterically hindering the assembly of the transcription initiation complex.
- Alternative Names
- Regulatory protein E2; E2
- Gene ID
- 1489080
- UniProt ID
- P03120
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-118 | Recombinant Rat Anti-HCV E2 Antibody (3/11) | WB, ELISA, Neut, FuncS | IgG |
| PABL-119 | Recombinant Human Anti-HCV E2 Antibody (HC33.1) | Neut, FuncS | IgG |
| PABL-120 | Recombinant Human Anti-HCV E2 Antibody (HC84-1) | WB, ELISA, Neut, FuncS | IgG |
| PABL-121 | Recombinant Mouse Anti-HCV E2 Antibody (HC84-27) | Neut, FuncS | IgG |
| PABL-122 | Recombinant Mouse Anti-HCV E2 Antibody (mAb12) | WB, ELISA, FuncS | IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-119 | Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HC33.1) | Neut, FuncS | Fab |
| PFBL-120 | Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HC84-1) | WB, ELISA, Neut, FuncS | Fab |
| PFBL-121 | Recombinant Mouse Anti-HCV E2 Antibody Fab Fragment (HC84-27) | Neut, FuncS | Fab |
| PFBL-122 | Recombinant Mouse Anti-HCV E2 Antibody Fab Fragment (mAb12) | WB, ELISA, FuncS | Fab |
| PFBL-123 | Recombinant Mouse Anti-HCV E2 Antibody Fab Fragment (mAb8) | WB, Neut, FuncS | Fab |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PNBL-019 | Recombinant Anti-HCV E2 VHH Single Domain Antibody (D03) | Inhib, FuncS | Llama VHH |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-184 | Recombinant Chimeric (Human/Mouse) Anti-HCV glycoprotein E2 Antibody Fab Fragment (mAb1:7) | Neut | Fab |
| HPAB-N0072-YC-S(P) | Recombinant Human Anti-E2 Antibody scFv Fragment (HC84.26.5D) | Neut, ELISA, FuncS | Human scFv |
| HPAB-N0074-YC-S(P) | Recombinant Humanized Anti-E2 Antibody scFv Fragment (TRN-1008) | Neut, ELISA, WB | Humanized scFv |
| HPAB-N0075-YC-S(P) | Recombinant Human Anti-E2 Antibody scFv Fragment (TRN-1007) | Neut, ELISA, WB | Human scFv |
| HPAB-2105-FY-S(P) | Human Anti-E2 Recombinant Antibody (clone D12); scFv Fragment | ELISA | Human scFv |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-020CT | Human Anti-HCV E2 Recombinant Antibody (AP33) | ELISA, IP, Neut, FC, WB | Human antibody |
| TAB-238CT-S(P) | Anti-HCV E2 Recombinant Antibody scFv Fragment (Y47F) | ELISA, WB | Human antibody |
| TAB-239CT-S(P) | Anti-HCV E2 Recombinant Antibody scFv Fragment (Y47W) | ELISA, WB | Human antibody |
| TAB-238CT-F(E) | Anti-HCV E2 Recombinant Antibody Fab Fragment (Y47F) | ELISA, WB | Human antibody |
| TAB-239CT-F(E) | Anti-HCV E2 Recombinant Antibody Fab Fragment (Y47W) | ELISA, WB | Human antibody |
MHC Tetramer for Virology
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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