DRB1*04:01/Human Tyrp1 (ISPNSVFSQWRVVCDSLEDYD) MHC Monomer (CAT#: MHC-YF058)
This product is a MHC monomer of biotinylated peptide/MHC complex composed Tyrp1-derived peptide of ISPNSVFSQWRVVCDSLEDYD sequence covering 277-297 and DRB1*04:01 molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
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Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SK-MEL-30
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/937/1291_B1_3_selected.jpg
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/937/1291_B1_3_selected.jpg
Figure 2 Skin
(Melanocytes
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/937/1995_B_9_1.jpg
(Melanocytes
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/937/1995_B_9_1.jpg
Figure 3 RNA cell line category: Cell line enriched (SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000107165-TYRP1/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000107165-TYRP1/subcellular
Specifications
- Allele
- DRB1*04:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- Tyrp1
- Antigen Species
- Human
- Peptide
- ISPNSVFSQWRVVCDSLEDYD
- Range
- 277-297
- Conjugate
- Biotin
- Application
- MHC Multimer
Target
- Antigen Introduction
- This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III.
- Alternative Names
- TRP; CAS2; CATB; GP75; OCA3; TRP1; TYRP; b-PROTEIN
- Gene ID
- 7306
- UniProt ID
- P17643
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1020 | Recombinant Anti-human TYRP1 Antibody | ELISA, WB, FC, FuncS | IgG |
| HPAB-0121-LSX | Human Anti-TYRP1 Recombinant Antibody (clone 20D7) | ELISA, FC | Human IgG1, κ |
| HPAB-0122-LSX | Human Anti-TYRP1 Recombinant Antibody (clone 20D7S) | ELISA, FC | Human IgG1, κ |
| FAMAB-1756CQ | Human Anti-TYRP1 Recombinant Antibody (clone TA99) | IP, WB, ELISA, FC, IF, IHC-Fr | Human IgG1 |
| VS13-YC1196 | Rabbit Anti-TYRP1 Recombinant Antibody (VS13-YC1196) | IHC-P | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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