DRB1*09:01/Human ESAT6 (MTEQQWNFAGIEAAA) MHC Tetramer
CAT#: MHC-YF880
This product is a MHC tetramer of biotinylated peptide/MHC complex composed ESAT6-derived peptide of MTEQQWNFAGIEAAA sequence covering 1-15 and DRB1*09:01 molecule. The pMHC tetramer recognizes CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Specifications
- Allele
- DRB1*09:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- ESAT6
- Antigen Species
- Mycobacterium tuberculosis
- Peptide
- MTEQQWNFAGIEAAA
- Range
- 1-15
- Application
- FCM
Target
- Antigen Introduction
- A secreted protein that plays a number of roles in modulating the host's immune response to infection as well as being responsible for bacterial escape into the host cytoplasm. Acts as a strong host (human) T-cell antigen. Inhibits IL-12 p40 (IL12B) and TNF-alpha expression by infected host (mouse) macrophages, reduces the nitric oxide response by about 75%.
- Alternative Names
- 6 kDa early secretory antigenic target; ESAT-6; esxA; esaT6; Rv3875; MTV027.10
- Gene ID
- 886209
- UniProt ID
- P9WNK7
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See other products for "ESAT6"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0649 | PE-H-2Kk/M. tuberculosis ESAT6 (VESTAGSL) MHC Tetramer | FCM, IHC | |
| MHC-CN0650 | APC-H-2Kk/M. tuberculosis ESAT6 (VESTAGSL) MHC Tetramer | FCM, IHC | |
| MHC-CN0651 | FITC-H-2Kk/M. tuberculosis ESAT6 (VESTAGSL) MHC Tetramer | FCM, IHC | |
| MHC-CN0652 | H-2Kk/M. tuberculosis ESAT6 (VESTAGSL) MHC Tetramer | FCM, IHC | |
| MHC-CN0653 | PE-A*24:02/M. tuberculosis ESAT6 (AYQGVQQKV) MHC Tetramer | FCM, IHC |
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